8-(3-nitro-4-hydroxyphenyl)-4,4-difluoro-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-s-indacene

Base Information

Chemical Name:8-(3-nitro-4-hydroxyphenyl)-4,4-difluoro-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-s-indacene
CAS No.:1181844-40-5
Molecular Formula:C₁₉H₁₈BF₂N₃O₃
Molecular Weight:385.178
Hs Code.:

Synonyms:8-(3-nitro-4-hydroxyphenyl)-4,4-difluoro-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-s-indacene

Suppliers and Price of 8-(3-nitro-4-hydroxyphenyl)-4,4-difluoro-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-s-indacene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 8-(3-nitro-4-hydroxyphenyl)-4,4-difluoro-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-s-indacene

Chemical Property:

Melting Point:>200 °C(Solv: chloroform (67-66-3); hexane (110-54-3))

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 8-(3-nitro-4-hydroxyphenyl)-4,4-difluoro-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-s-indacene

There total 3 articles about 8-(3-nitro-4-hydroxyphenyl)-4,4-difluoro-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-s-indacene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 19.07%

: 625-82-1
2,4-dimethyl-1H-pyrrole

: 3011-34-5
4-hydroxy-3-nitrobenzaldehyde

: 109-63-7
boron trifluoride diethyl etherate

: 1181844-40-5
8-(3-nitro-4-hydroxyphenyl)-4,4-difluoro-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-s-indacene

Guidance literature:: With catalyst: trifluoroacetic acid; 2,3-dichloro-5,6-dicyanoquinone; triethyl amine; In dichloromethane; 1 drop of CF3COOH was added to a soln. of pyrrole- and benzadehyde-compounds in CH2Cl2 under N2, stirred for 4 h at ambient temp. in the dark, quinone-compound was added, 30 min stirring, (C2H5)3N was added, after 5 min borate was added, 40 min stirring; the soln. was washed with water and brine, dried over MgSO4, concd. at reduced pressure, silica gel flash column chromy. (10% ethyl acetate-petroleum ether), recrystd. from CHCl3-hexane; elem. anal.;
DOI:10.1039/b902912e

Reference yield: 19.0%

: 625-82-1
2,4-dimethyl-1H-pyrrole

: 3011-34-5
4-hydroxy-3-nitrobenzaldehyde

: 1181844-40-5
8-(3-nitro-4-hydroxyphenyl)-4,4-difluoro-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-s-indacene

Guidance literature:: 2,4-dimethyl-1H-pyrrole; 4-hydroxy-3-nitrobenzaldehyde; With trifluoroacetic acid; In dichloromethane; at 20 ℃; Inert atmosphere;

With 2,3-dicyano-5,6-dichloro-p-benzoquinone; In dichloromethane; for 0.5h; Inert atmosphere;

With boron trifluoride diethyl etherate; triethylamine; for 0.75h; Inert atmosphere;
DOI:10.1039/b926300d

Reference yield:

: C₁₉H₁₉N₃O₃

: 1181844-40-5
8-(3-nitro-4-hydroxyphenyl)-4,4-difluoro-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-s-indacene

Guidance literature:: C₁₉H₁₉N₃O₃; With triethylamine; In dichloromethane; for 0.0833333h; Inert atmosphere;

With boron trifluoride diethyl etherate; In dichloromethane; for 0.666667h; Inert atmosphere;
DOI:10.1039/b902912e