Tiglic Anhydride

Base Information

• Chemical Name: Tiglic Anhydride
• CAS No.: 14316-68-8
• Molecular Formula: C10H14 O3
• Molecular Weight: 182.22
• Hs Code.: 2916190090
• European Community (EC) Number: 678-620-1
• Nikkaji Number: J534.171J
• Wikidata: Q76416563
• Mol file: 14316-68-8.mol

Synonyms:Tiglic Anhydride;14316-68-8;2-Methylcrotonic Anhydride;TIGLICANHYDRIDE;[(E)-2-methylbut-2-enoyl] (E)-2-methylbut-2-enoate;(E)-2-Methyl-2-butenoic Anhydride;(E)-2-methylbut-2-enoic anhydride;SCHEMBL432664;SCHEMBL432665;LIHLSLRANKCHLV-KQQUZDAGSA-N;MFCD00143614;AKOS025296266;PHENYLETHYLBETA-D-GLUCOPYRANOSIDE;BS-23866;CS-0207709;T1383;T71770;{2-[trans-2-(4-Fluorophenyl)vinyl]-3-nitrophenyl}-1-pyrrolidinylmethanone

Chemical Property of Tiglic Anhydride

Chemical Property:

• Refractive Index: 1.4800 to 1.4830
• Boiling Point: 278.546oC at 760 mmHg
• Flash Point: 119.788oC
• PSA: 43.37000
• Density: 1.03
• LogP: 1.98860
• XLogP3: 2.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 182.094294304
• Heavy Atom Count: 13
• Complexity: 244

Purity/Quality:

98%,99%, ^*data from raw suppliers

Tiglic Anhydride >98.0%(T) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC=C(C)C(=O)OC(=O)C(=CC)C
• Isomeric SMILES: C/C=C(/C(=O)OC(=O)/C(=C/C)/C)\C

Technology Process of Tiglic Anhydride

There total 14 articles about Tiglic Anhydride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

Tiglic acid (80-59-1) + (E)-2-methylbut-2-enoyl chloride (35660-94-7) → (E)-2-methyl-2-butenoic anhydride (14316-68-8)

Guidance literature:

With pyridine;

DOI:10.1002/hlca.19830660744

Reference yield: 66.0%

Tiglic acid (80-59-1) → (E)-2-methyl-2-butenoic anhydride (14316-68-8) + 5,6,8-trimethoxy-3,4,7-trimethylisocoumarin (134255-80-4)

Guidance literature:

With trifluoroacetic anhydride; for 64h; Ambient temperature; in presence of 2,3,6-trimethoxytoluene;

Reference yield: 66.0%

Tiglic acid (80-59-1) + 2,3,6-trimethoxytoluene (25576-97-0) → (E)-2-methyl-2-butenoic anhydride (14316-68-8) + 5,6,8-trimethoxy-3,4,7-trimethylisocoumarin (134255-80-4)

Guidance literature:

With air; trifluoroacetic anhydride; for 64h; Product distribution; Mechanism; Ambient temperature; other times, or with 18O₂, or without oxygen;

upstream raw materials:

(E)-2-methylbut-2-enoyl chloride

tiglic acid sodium salt

Tiglic acid

2,3,6-trimethoxytoluene

Downstream raw materials:

geiparvarin

atripliciolide tiglate