2,2-Bis(phenylthio)propane

Base Information

• Chemical Name: 2,2-Bis(phenylthio)propane
• CAS No.: 14252-46-1
• Molecular Formula: C15H16 S2
• Molecular Weight: 260.424
• Hs Code.: 2930909090
• DSSTox Substance ID: DTXSID80456703
• Nikkaji Number: J678.894G
• Wikidata: Q82279259
• Mol file: 14252-46-1.mol

Synonyms:2,2-bis(phenylthio)propane;2-phenylsulfanylpropan-2-ylsulfanylbenzene;14252-46-1;2,2-bisphenylthiopropane;SCHEMBL1107766;DTXSID80456703;1,1'-(Propane-2,2-diyldisulfanediyl)dibenzene

Chemical Property of 2,2-Bis(phenylthio)propane

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.632
• Boiling Point: 409.535°C at 760 mmHg
• Flash Point: 181.442°C
• PSA: 50.60000
• Density: 1.142g/cm³
• LogP: 5.30710
• XLogP3: 5.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 260.06934286
• Heavy Atom Count: 17
• Complexity: 191

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(SC1=CC=CC=C1)SC2=CC=CC=C2

Technology Process of 2,2-Bis(phenylthio)propane

There total 9 articles about 2,2-Bis(phenylthio)propane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

1,1-bis(phenylthio)ethane (13307-56-7) + methyl iodide (74-88-4) → 2,2-bis(phenylthio)propane (14252-46-1)

Guidance literature:

With n-butyllithium; N,N,N,N,-tetramethylethylenediamine; In hexane; at -5 - 0 ℃; for 1h;

Reference yield: 90.0%

thiophenol (108-98-5) + 2,2-dimethoxy-propane (77-76-9) → 2,2-bis(phenylthio)propane (14252-46-1)

Guidance literature:

With diethyl ether; lithium perchlorate; at 28 ℃; for 0.25h;

DOI:10.1021/jo00095a049

Reference yield: 73.0%

thiophenol (108-98-5) + acetone (67-64-1) → 2,2-bis(phenylthio)propane (14252-46-1)

Guidance literature:

With chloro-trimethyl-silane; In chloroform; for 1h; Ambient temperature;

DOI:10.1016/S0040-4020(01)85652-0

upstream raw materials:

thiophenol

acetone

phenylthiotrimethylsilane

4,4-Dimethyl-5-trimethylstannanyl-pentan-2-one

Downstream raw materials:

isopropenyl phenyl sulfide

2-methyl-6-phenylhexan-3-one

3-Phenylmercapto-but-3-en-1-in

4-t-Butoxy-3-phenylmercaptobuta-1,2-dien

Refernces

• 1、 Braga,Silveira,Dornelles,Zeni,Galarza,Wessjohann. "Catalyst-dependent selective synthesis of O/S- and S/S-acetals from enol ethers". . p. 3155 - 3162. Retrieved 2007/10/02.
• 2、 Saraswathy, V. Geetha,Sankararaman, S.. "Chemoselective Protection of Aldehydes as Dithioacetals in Lithium Perchlorate-Diethyl Ether Medium. Evidence for the Formation of Oxocarbenium Ion Intermediate from Acetals". . p. 4665 - 4670. Retrieved 2007/10/02.