N-(1-adamantyl)-2-nitroaniline

Base Information

• Chemical Name: N-(1-adamantyl)-2-nitroaniline
• CAS No.: 160917-92-0
• Molecular Formula: C₁₆H₂₀N₂O₂
• Molecular Weight: 272.347
• Mol file: 160917-92-0.mol

Synonyms:N-(1-adamantyl)-2-nitroaniline

Chemical Property of N-(1-adamantyl)-2-nitroaniline

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(1-adamantyl)-2-nitroaniline

There total 5 articles about N-(1-adamantyl)-2-nitroaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

1-Adamantanamine (768-94-5) + ortho-nitrofluorobenzene (1493-27-2,127723-77-7) → N-(1-adamantyl)-2-nitroaniline (160917-92-0)

Guidance literature:

With potassium fluoride; In N,N-dimethyl-formamide; at 170 ℃; for 12h; Inert atmosphere; Sealed tube;

DOI:10.1021/om5012616

Reference yield: 75.0%

adamantane (281-23-2) + 2-nitro-aniline (88-74-4) → N-(1-adamantyl)-2-nitroaniline (160917-92-0)

Guidance literature:

adamantane; With 2AlBr₃*CBr₄; In dibromomethane;

2-nitro-aniline; In dibromomethane; at 0 ℃; for 1h; regioselective reaction;

DOI:10.1016/j.mencom.2010.09.005

Reference yield: 61.4%

1-adamantyl trifluoroacetate (58652-54-3) + 2-nitro-aniline (88-74-4) → N-(1-adamantyl)-2-nitroaniline (160917-92-0) + 1-(4-amino-3-nitrophenyl)adamantane (59974-48-0)

Guidance literature:

With trifluoroacetic acid; at 18 - 20 ℃; for 120h; regioselective reaction;

DOI:10.1134/S1070363210030321

upstream raw materials:

1-adamanthanol

2-nitro-aniline

carbon monoxide

adamantane