Pangamic acid

Base Information

• Chemical Name: Pangamic acid
• CAS No.: 11006-56-7
• Molecular Formula: C₁₀H₁₉NO₈
• Molecular Weight: 281.263
• Mol file: 11006-56-7.mol

Synonyms:Vitamin B15

Chemical Property of Pangamic acid

Chemical Property:

• PSA: 147.76000
• LogP: -1.82340

Purity/Quality:

99% , ^*data from raw suppliers

PANGAMIC ACID 98.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Description: Pangamic acid, also called pangamate, is the name given to the chemical compound described as d-glucono dimethyl amino acetic acid, initially promoted by Ernst T. Krebs, Sr. and his son Ernst T. Krebs, Jr. as a medicinal compound for use in treatment of a wide range of diseases. They also termed this chemical "Vitamin B15", though it is not a true vitamin, has no nutritional value, has no known use in the treatment of any disease and has been called a "quack remedy." Although a number of compounds labelled "pangamic acid" have been studied or sold, no chemical compound, including those claimed by the Krebses to be pangamic acid, has been scientifically verified to have the characteristics that defined the original description of the compound.

Technology Process of Pangamic acid

There total 3 articles about Pangamic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

dimethylaminoacetic acid (1118-68-9) + gluconic acid (526-95-4) → pangamic acid (20858-86-0,11006-56-7,12770-30-8,304-56-3)

Guidance literature:

With hydrogenchloride;

Reference yield:

dimethyl amine (124-40-3) + chloroacetic acid (79-11-8) + D-Glucono-1,5-lactone (90-80-2,1335-57-5,4253-68-3) → pangamic acid (20858-86-0,11006-56-7,12770-30-8,304-56-3)

Guidance literature:

With hydrogenchloride;

Reference yield:

chloroacetyl chloride (79-04-9) + D-Glucono-1,5-lactone (90-80-2,1335-57-5,4253-68-3) → pangamic acid (20858-86-0,11006-56-7,12770-30-8,304-56-3)

Guidance literature:

Erwaermen des Reaktionsprodukts mit H₂O und Behandeln des Reaktionsgemisches mit Dimethylamin;

upstream raw materials:

dimethylaminoacetic acid

gluconic acid

dimethyl amine

chloroacetic acid