CHOLESTANOL ACETATE

Base Information

• Chemical Name: CHOLESTANOL ACETATE
• CAS No.: 1255-88-5
• Molecular Formula: C29H50 O2
• Molecular Weight: 430.715
• Mol file: 1255-88-5.mol

Synonyms:5a-Cholestan-3b-ol, acetate (8CI); 5a-Cholestanol, acetate (7CI);Cholestanol acetate (6CI); 3b-Acetoxy-5a-cholestane;5a-Cholest-2-en-3-ol 3-acetate; 5a-Cholestan-3b-yl acetate; Cholestan-3b-yl acetate

Chemical Property of CHOLESTANOL ACETATE

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 96-97 °C
• Refractive Index: 1.507
• Boiling Point: 446.344°C at 760 mmHg
• Flash Point: 249.847°C
• PSA: 26.30000
• Density: 0.986g/cm³
• LogP: 8.03940

Purity/Quality:

98% ^*data from raw suppliers

CHOLESTANOL ACETATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of CHOLESTANOL ACETATE

There total 5 articles about CHOLESTANOL ACETATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

trifluoroacetoxy-3β 5α-cholestane (2839-20-5) → cholestane (481-21-0) + 5α-cholestan-3β-yl acetate (1255-88-5) + monofluoroacetoxy-3β 5α-cholestane (97509-94-9) + difluoroacetoxy-3β 5α-cholestane (97509-93-8)

Guidance literature:

In N,N,N,N,N,N-hexamethylphosphoric triamide; at 50 ℃; Yield given. Yields of byproduct given; Irradiation;

DOI:10.1016/S0040-4039(00)61882-8

Reference yield:

hydrogenchloride (7647-01-0,15364-23-5) + Cholesteryl acetate (604-35-3) + acetic acid (64-19-7,77671-22-8) → cholestane (481-21-0) + 5α-cholestan-3β-yl acetate (1255-88-5)

Guidance literature:

Hydrogenation;

Reference yield:

silver(I) acetate (563-63-3) + sodium (20R)-5α-cholestan-3β-yl sulfate (107584-99-6) + acetic acid (64-19-7,77671-22-8) → Cholestanol (80-97-7) + 5α-cholestan-3β-yl acetate (1255-88-5)

Guidance literature:

DOI:10.1021/ja01184a040

upstream raw materials:

di-(5α-cholestanyl-(3β))-sulfite

silver(I) acetate

acetic acid

sodium (20R)-5α-cholestan-3β-yl sulfate

Downstream raw materials:

(3S,5S,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)hexadecahydro-1H-cyclopenta[a]phenanthren-3-yl methanesulfonate

3β-acetoxy-5α-androstan-17-one

Epiandrosterone

cholestane

Refernces

• 1、 Barrett, Anthony G. M.,Read, Roger W.,Barton, Derek H. R.. "Reactions of Relevance to the Chemistry of Aminoglycoside Antibiotics. Part 13. A Novel Synthesis of Benzyl Ethers". . p. 2184 - 2190. Retrieved 2007/10/02.