C₂₉H₄₄BrOPSi

Base Information

• Chemical Name: C₂₉H₄₄BrOPSi
• CAS No.: 862852-62-8
• Molecular Formula: C₂₉H₄₄BrOPSi
• Molecular Weight: 547.631
• Mol file: 862852-62-8.mol

Synonyms:C₂₉H₄₄BrOPSi

Chemical Property of C₂₉H₄₄BrOPSi

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₉H₄₄BrOPSi

There total 5 articles about C₂₉H₄₄BrOPSi which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

chloro-trimethyl-silane (75-77-4) + [(dibromomethylene)(2,4,6-tri-tertbutylphenyl)phosphine] (100281-23-0) + benzaldehyde (100-52-7) → C29H44BrOPSi (862852-62-8)

Guidance literature:

[(dibromomethylene)(2,4,6-tri-tertbutylphenyl)phosphine]; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.25h; Inert atmosphere; Schlenk technique;

benzaldehyde; In tetrahydrofuran; hexane; at -78 ℃; for 0.25h; Inert atmosphere; Schlenk technique;

chloro-trimethyl-silane; In tetrahydrofuran; hexane; at 0 - 40 ℃; for 3h; Inert atmosphere; Schlenk technique;

DOI:10.1002/cctc.201402158

Reference yield: 70.0%

chloro-trimethyl-silane (75-77-4) + [(dibromomethylene)(2,4,6-tri-tertbutylphenyl)phosphine] (100281-23-0) + benzaldehyde (100-52-7) → 2-bromo-3-phenyl-1-(2,4,6-tri-tert-butylphenyl)-3-trimethylsiloxy-1-phospha-1-propene (862852-62-8)

Guidance literature:

[(dibromomethylene)(2,4,6-tri-tertbutylphenyl)phosphine]; With n-butyllithium; In tetrahydrofuran; hexane; at -100 ℃; for 0.166667h;

benzaldehyde; In tetrahydrofuran; hexane; at -100 - 20 ℃;

chloro-trimethyl-silane; In tetrahydrofuran; hexane; at 20 ℃; for 0.25h;

DOI:10.1246/bcsj.78.1142

Reference yield:

2,4,6-tri-t-butylphenylphosphonous dichloride (79074-00-3) → 2-bromo-3-phenyl-1-(2,4,6-tri-tert-butylphenyl)-3-trimethylsiloxy-1-phospha-1-propene (862852-62-8)

Guidance literature:

Multi-step reaction with 2 steps

1.1: LDA / -100 °C

2.1: n-BuLi / tetrahydrofuran; hexane / 0.17 h / -100 °C

2.2: tetrahydrofuran; hexane / -100 - 20 °C

2.3: 70 percent / tetrahydrofuran; hexane / 0.25 h / 20 °C

With n-butyllithium; lithium diisopropyl amide; In tetrahydrofuran; hexane;

DOI:10.1246/bcsj.78.1142

upstream raw materials:

chloro-trimethyl-silane

[(dibromomethylene)(2,4,6-tri-tertbutylphenyl)phosphine]

benzaldehyde

2,4,6-tri-t-butylphenylphosphonous dichloride

Downstream raw materials:

(Phenylethenyliden)(2,4,6-tri-tert-butylphenyl)phosphan

(E,E)-1,2-diphenyl-3,4-bis[(2,4,6-tri-tert-butylphenyl)phosphinidene]cyclobutene