Technology Process of (R)-O-benzyl-serine allyl ester
There total 4 articles about (R)-O-benzyl-serine allyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
toluene-4-sulfonic acid;
In
benzene;
at 100 ℃;
for 8h;
optical yield given as %ee;
Inert atmosphere;
DOI:10.1039/c0cc00607f
- Guidance literature:
-
Multi-step reaction with 3 steps
1: magnesium sulfate; triethylamine / methanol / 0 - 23 °C / Inert atmosphere
2: sodium tetrahydroborate / 12 h / 0 °C / Inert atmosphere
3: toluene-4-sulfonic acid / benzene / 8 h / 100 °C / Inert atmosphere
With
sodium tetrahydroborate; magnesium sulfate; toluene-4-sulfonic acid; triethylamine;
In
methanol; benzene;
DOI:10.1021/jo101638r
- Guidance literature:
-
Multi-step reaction with 3 steps
1: magnesium sulfate; triethylamine / methanol / 0 - 23 °C / Inert atmosphere
2: sodium tetrahydroborate / 12 h / 0 °C / Inert atmosphere
3: toluene-4-sulfonic acid / benzene / 8 h / 100 °C / Inert atmosphere
With
sodium tetrahydroborate; magnesium sulfate; toluene-4-sulfonic acid; triethylamine;
In
methanol; benzene;
DOI:10.1021/jo101638r
