Deacetylanisomycin

Base Information Edit

Chemical Name:Deacetylanisomycin
CAS No.:27958-06-1
Molecular Formula:C12H17 N O3
Molecular Weight:223.272
Hs Code.:2933990090
UNII:97W54EY1WU
DSSTox Substance ID:DTXSID40182238
Nikkaji Number:J797.077C
Mol file:27958-06-1.mol

Synonyms:Deacetylanisomycin;27958-06-1;(-)-Deacetylanisomycin;Anisomycin, deacetyl-;(2R,3S,4S)-2-((4-Methoxyphenyl)methyl)-3,4-pyrrolidinediol;DEACETYLANISOMYCIN FROM STREPTOMYCES*GRISEOLUS;97W54EY1WU;3,4-Pyrrolidinediol, 2-((4-methoxyphenyl)methyl)-, (2R,3S,4S)-;3,4-Pyrrolidinediol, 2-(p-methoxybenzyl)-, (2R,3S,4S)-(-)-;UNII-97W54EY1WU;(2R,3S,4S)-2-[(4-methoxyphenyl)methyl]pyrrolidine-3,4-diol;SCHEMBL5081415;DTXSID40182238;UMWAPBCLJQSOJX-WOPDTQHZSA-N;ANISOMYCIN DEACETYLANISOMYCIN;AKOS040741618;3,4-Pyrrolidinediol, 2-((4-methoxyphenyl)methyl)-, (2R-(2alpha,3alpha,4beta))-;ANISOMYCIN DEACETYLANISOMYCIN [MI];HY-111744;CS-0090664;Q27272040;(2R,3S,4S)-2-(4-Methoxybenzyl)pyrrolidine-3,4-diol;(2R, 3S, 4S)-2-[(4-methoxyphenyl)methyl]pyrrolidine-3, 4-diol;3,4-PYRROLIDINEDIOL, 2-((4-METHOXYPHENYL)METHYL)-, (2R-(2.ALPHA.,3.ALPHA.,4.BETA.))-

Suppliers and Price of Deacetylanisomycin

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Deacetylanisomycin
2mg
$ 426.00

TRC
Deacetylanisomycin
10mg
$ 415.00

Cayman Chemical
Deacetylanisomycin
5mg
$ 215.00

Cayman Chemical
Deacetylanisomycin
25mg
$ 968.00

American Custom Chemicals Corporation
DEACETYLANISOMYCIN 95.00%
5MG
$ 497.07

AK Scientific
Deacetylanisomycin
5mg
$ 368.00

Total 8 raw suppliers

Chemical Property of Deacetylanisomycin Edit

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:176-179°
Refractive Index:1.587
Boiling Point:390.693°C at 760 mmHg
PKA:9.2(at 25℃)
Flash Point:190.084°C
PSA：61.72000
Density:1.233g/cm³
LogP:0.26010
Storage Temp.:2-8°C
XLogP3:0.3
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:223.12084340
Heavy Atom Count:16
Complexity:216

Purity/Quality:

98%Min ^*data from raw suppliers

Deacetylanisomycin ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)CC2C(C(CN2)O)O
Isomeric SMILES:COC1=CC=C(C=C1)C[C@@H]2[C@@H]([C@H](CN2)O)O
Description Deacetylanisomycin is a derivative of the protein and DNA synthesis inhibitor anisomycin with antimalarial and anticancer activity. It inhibits the growth of the P. falciparum strains K1 and T9-96 in vitro (IC50s = 40.29 and 33.57 μM, respectively). Deacetylanisomycin is cytotoxic to LU99 lung carcinoma and MCF-7 breast cancer cells (IC50s = 23 and 34 μM, respectively). It has been used as a negative control for assessment of protein synthesis inhibitor activity in molluscan neurons.
Uses Deacetylanisomycin is the core structure of a family of dihydroxypyrrolidines produced by several species of Streptomyces. Anisomycin esters are potent inhibitors of protein synthesis. While considered inactive, deacetylanisomycin is a potent growth regulator in plants and its underlying pharmacology is poorly researched. This is all the more significant as anisomycin undergoes facile hydrolysis to deacetylanisomycin in polar solvents in vitro, and in vivo. Agricultural fungicide. Deacetylanisomycin is a potent inhibitor of protein synthesis.

Technology Process of Deacetylanisomycin

There total 79 articles about Deacetylanisomycin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%