pentafluorophenyl 4-(4-tert-butoxycarbonyl-piperazin-1-yl)-4-oxobutanoate

Base Information

Chemical Name:pentafluorophenyl 4-(4-tert-butoxycarbonyl-piperazin-1-yl)-4-oxobutanoate
CAS No.:329911-76-4
Molecular Formula:C₁₉H₂₁F₅N₂O₅
Molecular Weight:452.378
Hs Code.:

Synonyms:pentafluorophenyl 4-(4-tert-butoxycarbonyl-piperazin-1-yl)-4-oxobutanoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of pentafluorophenyl 4-(4-tert-butoxycarbonyl-piperazin-1-yl)-4-oxobutanoate

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Technology Process of pentafluorophenyl 4-(4-tert-butoxycarbonyl-piperazin-1-yl)-4-oxobutanoate

There total 2 articles about pentafluorophenyl 4-(4-tert-butoxycarbonyl-piperazin-1-yl)-4-oxobutanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 771-61-9
2,3,4,5,6-pentafluorophenol

: 288851-44-5
4-(4-tert-butoxycarbonyl-piperazin-1-yl)-4-oxobutanoic acid

: 329911-76-4
pentafluorophenyl 4-(4-tert-butoxycarbonyl-piperazin-1-yl)-4-oxobutanoate

Guidance literature:: With dicyclohexyl-carbodiimide; In tetrahydrofuran; at 0 ℃; for 0.666667h;

Reference yield:

: 57260-71-6
1-t-Butoxycarbonylpiperazine

: 329911-76-4
pentafluorophenyl 4-(4-tert-butoxycarbonyl-piperazin-1-yl)-4-oxobutanoate

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / CHCl₃ / 0.33 h

2: 84 percent / 1,3-dicyclohexylcarbodiimide / tetrahydrofuran / 0.67 h / 0 °C

With dicyclohexyl-carbodiimide; In tetrahydrofuran; chloroform;