2-Hydroxy-3-phenylpropanoic acid methyl ester

Base Information

• Chemical Name: 2-Hydroxy-3-phenylpropanoic acid methyl ester
• CAS No.: 13674-16-3
• Molecular Formula: C10H12O3
• Molecular Weight: 180.203
• Hs Code.: 2918199090
• Mol file: 13674-16-3.mol

Synonyms:2-Hydroxy-3-phenylpropanoic acid methyl ester;Papuline;Benzenepropanoic acid, a-hydroxy-, Methyl ester

Chemical Property of 2-Hydroxy-3-phenylpropanoic acid methyl ester

Chemical Property:

• Melting Point: 47.5-48.5 °C
• Boiling Point: 155 °C(Press: 17 Torr)
• PKA: 13.00±0.20(Predicted)
• PSA: 46.53000
• Density: 1.150±0.06 g/cm3(Predicted)
• LogP: 0.76300
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

Methyl2-Hydroxy-3-Phenylpropanoate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Hydroxy-3-phenylpropanoic acid methyl ester

There total 44 articles about 2-Hydroxy-3-phenylpropanoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methanol (67-56-1) + phenyllactic acid (828-01-3) → methyl 2-hydroxy-3-phenylpropanoate (13674-16-3)

Guidance literature:

With sulfuric acid; at 20 - 30 ℃;

Reference yield: 100.0%

phenyllactic acid (828-01-3) + methyl iodide (74-88-4) → methyl 2-hydroxy-3-phenylpropanoate (13674-16-3)

Guidance literature:

With caesium carbonate; In N-methyl-acetamide; water;

Reference yield: 98.0%

L-3-phenyllactic acid (20312-36-1) → methyl 2-hydroxy-3-phenylpropanoate (13674-16-3)

Guidance literature:

With p-toluenesulfonic acid monohydrate; silica gel; In methanol;

upstream raw materials:

phenyllactic acid

methanol

3-phenylpropanoic acid methyl ester

methyl phenylpyruvate

Downstream raw materials:

α-Benzyloxyhydrozimtsaeuremethylester

α-Ethoxyhydrozimtsaeuremethylester

C₁₈H₂₄N₂O₆

4-Benzyl-5-methoxy-[1,2,3]oxadiazole-2,3-dicarboxylic acid diisopropyl ester