3,4-diphenyl-1-tosylimidazolidine

Base Information

• Chemical Name: 3,4-diphenyl-1-tosylimidazolidine
• CAS No.: 97511-33-6
• Molecular Formula: C₂₂H₂₂N₂O₂S
• Molecular Weight: 378.495
• Mol file: 97511-33-6.mol

Synonyms:3,4-diphenyl-1-tosylimidazolidine

Chemical Property of 3,4-diphenyl-1-tosylimidazolidine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,4-diphenyl-1-tosylimidazolidine

There total 13 articles about 3,4-diphenyl-1-tosylimidazolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 4-methyl-N-(2-phenyl-2-(phenylamino)ethyl)benzenesulfonamide (105159-32-8) → 3,4-diphenyl-1-tosylimidazolidine (97511-33-6)

Guidance literature:

In ethanol; water; for 3h; Heating;

DOI:10.1016/S0040-4020(01)87547-5

Reference yield: 91.0%

4-methyl-N-(2-(methyl(phenyl)amino)-2-phenylethyl)benzenesulfonamide (97511-34-7) → 3,4-diphenyl-1-tosylimidazolidine (97511-33-6)

Guidance literature:

4-methyl-N-(2-(methyl(phenyl)amino)-2-phenylethyl)benzenesulfonamide; With copper(II) bis(trifluoromethanesulfonate); In 1,2-dichloro-ethane; at 60 ℃; for 1h;

With tert.-butylhydroperoxide; In 1,2-dichloro-ethane; at 60 ℃; for 1.5h;

DOI:10.1021/acs.orglett.6b03458

Reference yield: 86.0%

N-(p-tolylsulfonyl)-2-phenylaziridine (24395-14-0) + N-methylaniline (100-61-8) → 3,4-diphenyl-1-tosylimidazolidine (97511-33-6)

Guidance literature:

N-(p-tolylsulfonyl)-2-phenylaziridine; N-methylaniline; With copper(II) bis(trifluoromethanesulfonate); In 1,2-dichloro-ethane; at 60 ℃; for 1h;

With tert.-butylhydroperoxide; In 1,2-dichloro-ethane; at 60 ℃; for 5h; Reagent/catalyst; Solvent; Catalytic behavior;

DOI:10.1021/acs.orglett.6b03458

upstream raw materials:

formaldehyd

4-methyl-N-(2-phenyl-2-(phenylamino)ethyl)benzenesulfonamide

N-(2-amino-1-phenylethyl)benzenamine

NSC 4573

Downstream raw materials:

N-{2-[2,4-Bis-(6-amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidin-5-ylmethyl)-phenylamino]-2-phenyl-ethyl}-4-methyl-benzenesulfonamide

4-methyl-N-(2-phenyl-2-(phenylamino)ethyl)benzenesulfonamide

C₂₅H₂₆N₆O₄

N-{2-[4-(1,3-Dimethyl-2,4-dioxo-6-phenylamino-1,2,3,4-tetrahydro-pyrimidin-5-ylmethyl)-phenylamino]-2-phenyl-ethyl}-4-methyl-benzenesulfonamide