5-(trimethylsilyl)-7-phenyl-5-(phenylsulfonyl)heptanyl p-toluenesulfonyl disulfide

Base Information

• Chemical Name: 5-(trimethylsilyl)-7-phenyl-5-(phenylsulfonyl)heptanyl p-toluenesulfonyl disulfide
• CAS No.: 130220-16-5
• Molecular Formula: C₂₉H₃₈O₄S₄Si
• Molecular Weight: 606.968
• Mol file: 130220-16-5.mol

Synonyms:5-(trimethylsilyl)-7-phenyl-5-(phenylsulfonyl)heptanyl p-toluenesulfonyl disulfide

Chemical Property of 5-(trimethylsilyl)-7-phenyl-5-(phenylsulfonyl)heptanyl p-toluenesulfonyl disulfide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-(trimethylsilyl)-7-phenyl-5-(phenylsulfonyl)heptanyl p-toluenesulfonyl disulfide

There total 6 articles about 5-(trimethylsilyl)-7-phenyl-5-(phenylsulfonyl)heptanyl p-toluenesulfonyl disulfide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

potassium thiotosylate (28519-50-8) + 7-iodo-3-(trimethylsilyl)-1-phenyl-3-(phenylsulfonyl)heptane (130220-10-9) → 3-(trimethylsilyl)-1-phenyl-3-(phenylsulfonyl)-7-p-(toluenethiosulfonyl)heptane (130220-13-2) + 5-(trimethylsilyl)-7-phenyl-5-(phenylsulfonyl)heptanyl p-toluenesulfonyl disulfide (130220-16-5)

Guidance literature:

In water; acetone; for 20h; Ambient temperature;

Reference yield:

((3-phenylpropyl)sulfonyl)benzene (17494-61-0) → 5-(trimethylsilyl)-7-phenyl-5-(phenylsulfonyl)heptanyl p-toluenesulfonyl disulfide (130220-16-5)

Guidance literature:

Multi-step reaction with 3 steps

1: 1.) hexamethylphosphoric triamide (HMPA), n-BuLi / 1.) THF, hexane, -78 deg C, 15 min, 2.) from -78 deg C to 25 deg C

2: 1.) hexamethylphosphoric triamide (HMPA), n-BuLi / 1.) THF, -78 deg C, 15 min, 2.) from -78 deg C to RT, 4 h

3: 16 percent / acetone; H₂O / 20 h / Ambient temperature

With N,N,N,N,N,N-hexamethylphosphoric triamide; n-butyllithium; In water; acetone;

Reference yield:

phenyl 3-phenylpropyl sulfide (30134-12-4) → 5-(trimethylsilyl)-7-phenyl-5-(phenylsulfonyl)heptanyl p-toluenesulfonyl disulfide (130220-16-5)

Guidance literature:

Multi-step reaction with 4 steps

1: 80percent m-chloroperbenzoic acid / CH₂Cl₂ / 25 °C

2: 1.) hexamethylphosphoric triamide (HMPA), n-BuLi / 1.) THF, hexane, -78 deg C, 15 min, 2.) from -78 deg C to 25 deg C

3: 1.) hexamethylphosphoric triamide (HMPA), n-BuLi / 1.) THF, -78 deg C, 15 min, 2.) from -78 deg C to RT, 4 h

4: 16 percent / acetone; H₂O / 20 h / Ambient temperature

With N,N,N,N,N,N-hexamethylphosphoric triamide; n-butyllithium; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; water; acetone;

upstream raw materials:

potassium thiotosylate

7-iodo-3-(trimethylsilyl)-1-phenyl-3-(phenylsulfonyl)heptane

((3-phenylpropyl)sulfonyl)benzene

1-Bromo-3-phenylpropane