4-Chloro-2,6-diacetylpyridine

Base Information

Chemical Name:4-Chloro-2,6-diacetylpyridine
CAS No.:195967-10-3
Molecular Formula:C9H8ClNO2
Molecular Weight:197.62
Hs Code.:2933399090
DSSTox Substance ID:DTXSID90445345
Nikkaji Number:J877.061A
Wikidata:Q82263717
Mol file:195967-10-3.mol

Synonyms:195967-10-3;1,1'-(4-Chloropyridine-2,6-diyl)diethanone;4-CHLORO-2,6-DIACETYLPYRIDINE;2,6-Diacetyl-4-chloropyridine;1-(6-ACETYL-4-CHLOROPYRIDIN-2-YL)ETHANONE;1-(6-ACETYL-4-CHLOROPYRIDIN-2-YL)ETHAN-1-ONE;Ethanone,1,1'-(4-chloro-2,6-pyridinediyl)bis-;Ethanone, 1,1'-(4-chloro-2,6-pyridinediyl)bis-;SCHEMBL4574258;DTXSID90445345;HVWKKCHGZJFEQD-UHFFFAOYSA-N;AKOS006308040;AB62707;1-(6-Acetyl-4-chloro-pyridin-2-yl)-ethanone;EN300-8087227;A850760;1,1'-(4-Chloropyridine-2,6-diyl)di(ethan-1-one);J-400578

Suppliers and Price of 4-Chloro-2,6-diacetylpyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemenu
1,1''-(4-Chloropyridine-2,6-diyl)diethanone 95%
1g
$ 729.00

Atlantic Research Chemicals
4-Chloro-2,6-diacetylpyridine 95%
1gm:
$ 844.76

American Custom Chemicals Corporation
4-CHLORO-2,6-DIACETYLPYRIDINE 95.00%
5MG
$ 496.96

Alichem
1,1'-(4-Chloropyridine-2,6-diyl)diethanone
1g
$ 803.40

Total 9 raw suppliers

Chemical Property of 4-Chloro-2,6-diacetylpyridine

Chemical Property:

Boiling Point:339.553 °C at 760 mmHg
PKA:-1.06±0.10(Predicted)
Flash Point:159.156 °C
PSA：47.03000
Density:1.253 g/cm³
LogP:2.14020
XLogP3:1.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:197.0243562
Heavy Atom Count:13
Complexity:208

Purity/Quality:

97% ^*data from raw suppliers

1,1''-(4-Chloropyridine-2,6-diyl)diethanone 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)C1=CC(=CC(=N1)C(=O)C)Cl

Technology Process of 4-Chloro-2,6-diacetylpyridine

There total 10 articles about 4-Chloro-2,6-diacetylpyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 269054-10-6
4-chloro-2,6-bis-(diazoacetyl)pyridine

: 195967-10-3
1,1'-(4-chloropyridine-2,6-diyl)diethanone

Guidance literature:: With hydrogen iodide; In dichloromethane; for 48h;
DOI:10.1016/S0040-4020(00)00104-6

Reference yield: 90.0%

: 1422463-80-6
4-chloro-2,6-bis(1-pyrrolidinylcarbonyl)pyridine

: 676-58-4
methylmagnesium chloride

: 195967-10-3
1,1'-(4-chloropyridine-2,6-diyl)diethanone

Guidance literature:: 4-chloro-2,6-bis(1-pyrrolidinylcarbonyl)pyridine; methylmagnesium chloride; In tetrahydrofuran; at 0 - 20 ℃; for 2h;

With hydrogenchloride; In tetrahydrofuran; water; at 0 ℃;
DOI:10.1016/j.tetlet.2012.11.004

Reference yield: 25.0%

: 7379-35-3
4-chlorpyridine hydrochloride

: 127-17-3
2-oxo-propionic acid

: 195967-10-3
1,1'-(4-chloropyridine-2,6-diyl)diethanone

Guidance literature:: 4-chlorpyridine hydrochloride; With sodium carbonate; In water; Inert atmosphere;

2-oxo-propionic acid; With ammonium peroxydisulfate; sulfuric acid; silver nitrate; In water; at 20 ℃; for 24h; Inert atmosphere;
DOI:10.1021/ic402469t