Technology Process of 5-(7-chloro-2-methyl-1,6-naphthyridin-3-yl)-2-fluoroaniline
There total 8 articles about 5-(7-chloro-2-methyl-1,6-naphthyridin-3-yl)-2-fluoroaniline which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium hydroxide;
In
ethanol;
at 60 ℃;
for 1h;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: triethylamine / dimethyl sulfoxide / 20 °C
2: trifluoroacetic acid / 50 °C
3: lithium aluminium tetrahydride / tetrahydrofuran / 0 - 20 °C / Inert atmosphere
4: manganese(IV) oxide / dichloromethane / 20 °C
5: potassium hydroxide / ethanol / 1 h / 60 °C
With
manganese(IV) oxide; lithium aluminium tetrahydride; triethylamine; trifluoroacetic acid; potassium hydroxide;
In
tetrahydrofuran; ethanol; dichloromethane; dimethyl sulfoxide;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: trifluoroacetic acid / 50 °C
2: lithium aluminium tetrahydride / tetrahydrofuran / 0 - 20 °C / Inert atmosphere
3: manganese(IV) oxide / dichloromethane / 20 °C
4: potassium hydroxide / ethanol / 1 h / 60 °C
With
manganese(IV) oxide; lithium aluminium tetrahydride; trifluoroacetic acid; potassium hydroxide;
In
tetrahydrofuran; ethanol; dichloromethane;
