Methyl 2-(2-methylbenzo[d]thiazol-6-yl)acetate

Base Information

Chemical Name:Methyl 2-(2-methylbenzo[d]thiazol-6-yl)acetate
CAS No.:188111-63-9
Molecular Formula:C₁₁H₁₁NO₂S
Molecular Weight:221.28
Hs Code.:
DSSTox Substance ID:DTXSID301282610
Mol file:188111-63-9.mol

Synonyms:188111-63-9;Methyl (2-methyl-1,3-benzothiazol-6-yl)acetate;6-Benzothiazoleaceticacid,2-methyl-,methylester(9CI);METHYL 2-(2-METHYL-1,3-BENZOTHIAZOL-6-YL)ACETATE;methyl 2-(2-methylbenzo[d]thiazol-6-yl)acetate;DTXSID301282610;Methyl 2-methyl-6-benzothiazoleacetate

Suppliers and Price of Methyl 2-(2-methylbenzo[d]thiazol-6-yl)acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 1 raw suppliers

Chemical Property of Methyl 2-(2-methylbenzo[d]thiazol-6-yl)acetate

Chemical Property:

PSA：67.43000
LogP:2.32020
XLogP3:2.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:221.05104977
Heavy Atom Count:15
Complexity:247

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NC2=C(S1)C=C(C=C2)CC(=O)OC

Technology Process of Methyl 2-(2-methylbenzo[d]thiazol-6-yl)acetate

There total 2 articles about Methyl 2-(2-methylbenzo[d]thiazol-6-yl)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 67-56-1
methanol

: 133178-71-9
2-(4-amino-3-iodophenyl)acetic acid

: 62-55-5
thioacetamide

: 188111-63-9
(2-Methyl-benzothiazol-6-yl)-acetic acid methyl ester

Guidance literature:: With 1,1'-bis-(diphenylphosphino)ferrocene; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; copper(II) oxide; In N,N-dimethyl-formamide; at 60 ℃; for 6h;
DOI:10.1021/jm960723m

Reference yield:

: 1197-55-3
4-aminophenylacetic acid

: 188111-63-9
(2-Methyl-benzothiazol-6-yl)-acetic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 56 percent / ICl / CH₂Cl₂

2: 0.51 g / 1,1'-bis(diphenylphosphino)ferrocene, CuO, tris(dibenzylideneacetone)dipalladium⁽⁰⁾ / dimethylformamide / 6 h / 60 °C

With 1,1'-bis-(diphenylphosphino)ferrocene; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; Iodine monochloride; copper(II) oxide; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm960723m