7-(benzyloxy)naphthalen-2-yl pivalate

Base Information

• Chemical Name: 7-(benzyloxy)naphthalen-2-yl pivalate
• CAS No.: 1122065-29-5
• Molecular Formula: C₂₂H₂₂O₃
• Molecular Weight: 334.415
• Mol file: 1122065-29-5.mol

Synonyms:7-(benzyloxy)naphthalen-2-yl pivalate

Chemical Property of 7-(benzyloxy)naphthalen-2-yl pivalate

Chemical Property:

Purity/Quality:

Safty Information:

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• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 7-(benzyloxy)naphthalen-2-yl pivalate

There total 1 articles about 7-(benzyloxy)naphthalen-2-yl pivalate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

7-(benzyloxy)-2-naphthol (118495-07-1) + pivaloyl chloride (3282-30-2) → 7-(benzyloxy)naphthalen-2-yl pivalate (1122065-29-5)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃;

DOI:10.1021/jacs.0c00283

Reference yield: 77.0%

7-(benzyloxy)naphthalen-2-yl pivalate (1122065-29-5) + phenyllithium (591-51-5) → 2-(benzyloxy)-7-phenylnaphthalene (1122065-43-3)

Guidance literature:

phenyllithium; With zinc(II) chloride; In tetrahydrofuran; dibutyl ether; at 20 ℃; for 0.5h; Inert atmosphere;

7-(benzyloxy)naphthalen-2-yl pivalate; With bis(tricyclohexylphosphine)nickel(II) dichloride; In tetrahydrofuran; dibutyl ether; N,N-dimethyl acetamide; at 70 ℃; for 2h; Inert atmosphere;

DOI:10.1002/anie.200803814

Reference yield: 55.0%

7-(benzyloxy)naphthalen-2-yl pivalate (1122065-29-5) + N-tert-butyl-1-(2-methoxyphenyl)methanimine (82632-38-0) → 2-(7-(benzyloxy)naphthalen-2-yl)benzaldehyde

Guidance literature:

7-(benzyloxy)naphthalen-2-yl pivalate; N-tert-butyl-1-(2-methoxyphenyl)methanimine; With chromium dichloride; magnesium; 4,4'-di-tert-butyl-2,2'-bipyridine; In tetrahydrofuran; at 40 ℃; for 48h; Inert atmosphere; Schlenk technique;

With hydrogenchloride; water; In tetrahydrofuran; at 20 ℃; for 0.5h; Inert atmosphere; Schlenk technique;

DOI:10.1021/jacs.0c00283

upstream raw materials:

7-(benzyloxy)-2-naphthol

pivaloyl chloride

Downstream raw materials:

2-(benzyloxy)-7-phenylnaphthalene