phenyl 2-(benzyloxy)-3-bromo-4-(dimethoxymethyl)-5-fluoro-6-methylbenzoate

Base Information

Chemical Name:phenyl 2-(benzyloxy)-3-bromo-4-(dimethoxymethyl)-5-fluoro-6-methylbenzoate
CAS No.:1254336-22-5
Molecular Formula:C₂₄H₂₂BrFO₅
Molecular Weight:489.338
Hs Code.:

Synonyms:phenyl 2-(benzyloxy)-3-bromo-4-(dimethoxymethyl)-5-fluoro-6-methylbenzoate

Suppliers and Price of phenyl 2-(benzyloxy)-3-bromo-4-(dimethoxymethyl)-5-fluoro-6-methylbenzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of phenyl 2-(benzyloxy)-3-bromo-4-(dimethoxymethyl)-5-fluoro-6-methylbenzoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of phenyl 2-(benzyloxy)-3-bromo-4-(dimethoxymethyl)-5-fluoro-6-methylbenzoate

There total 9 articles about phenyl 2-(benzyloxy)-3-bromo-4-(dimethoxymethyl)-5-fluoro-6-methylbenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 1253799-47-1
phenyl 2-(benzyloxy)-3-bromo-5-fluoro-4-formyl-6-methylbenzoate

: 149-73-5
trimethyl orthoformate

: 1254336-22-5
phenyl 2-(benzyloxy)-3-bromo-4-(dimethoxymethyl)-5-fluoro-6-methylbenzoate

Guidance literature:: With toluene-4-sulfonic acid; In methanol; at 20 ℃; Reflux;

Reference yield: 91.0%

: 67-56-1
methanol

: 1253799-47-1
phenyl 2-(benzyloxy)-3-bromo-5-fluoro-4-formyl-6-methylbenzoate

: 149-73-5
trimethyl orthoformate

: 1254336-22-5
phenyl 2-(benzyloxy)-3-bromo-4-(dimethoxymethyl)-5-fluoro-6-methylbenzoate

Guidance literature:: toluene-4-sulfonic acid; Reflux;

Reference yield:

: 1207285-03-7
phenyl 3-bromo-5-fluoro-2-hydroxy-6-methylbenzoate

: 1254336-22-5
phenyl 2-(benzyloxy)-3-bromo-4-(dimethoxymethyl)-5-fluoro-6-methylbenzoate

Guidance literature:: Multi-step reaction with 3 steps

1.1: potassium carbonate / acetone / 3 h / 0 - 50 °C

2.1: lithium diisopropyl amide; diisopropylamine; n-butyllithium / tetrahydrofuran / 0.17 h / -78 °C

2.2: 1 h / -78 - -20 °C

3.1: toluene-4-sulfonic acid / methanol / 20 °C / Reflux

With n-butyllithium; potassium carbonate; toluene-4-sulfonic acid; diisopropylamine; lithium diisopropyl amide; In tetrahydrofuran; methanol; acetone;