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p-fluorobenzyltrimethylammonium bromide

Base Information
  • Chemical Name:p-fluorobenzyltrimethylammonium bromide
  • CAS No.:333-45-9
  • Molecular Formula:Br*C10H15FN
  • Molecular Weight:248.138
  • Hs Code.:
p-fluorobenzyltrimethylammonium bromide

Synonyms:p-fluorobenzyltrimethylammonium bromide

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Chemical Property of p-fluorobenzyltrimethylammonium bromide
Chemical Property:
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Technology Process of p-fluorobenzyltrimethylammonium bromide

There total 1 articles about p-fluorobenzyltrimethylammonium bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
In tetrahydrofuran; ethanol; at 25 ℃; for 24h; Inert atmosphere;
DOI:10.1055/s-0035-1562344
Guidance literature:
With [1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene](3-chloropyridyl)palladium(ll) dichloride; potassium tert-butylate; In acetonitrile; at 70 ℃; for 12h; Schlenk technique; Inert atmosphere;
DOI:10.1016/j.jorganchem.2021.122176
Guidance literature:
p-fluorobenzyltrimethylammonium bromide; With potassium tert-butylate; In tetrahydrofuran; at 40 ℃; for 0.166667h; Inert atmosphere;
benzaldehyde; In tetrahydrofuran; at 40 ℃; for 3h; Overall yield = 94 %; diastereoselective reaction; Inert atmosphere;
DOI:10.1055/s-0035-1562344
upstream raw materials:

4-Fluorobenzyl bromide

trimethylamine

Downstream raw materials:

4-fluorobenzyl(4-methylphenyl)sulfane

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