N-methoxycarbonyl-3,4-dithiophenoylmaleimide

Base Information

• Chemical Name: N-methoxycarbonyl-3,4-dithiophenoylmaleimide
• CAS No.: 1442447-50-8
• Molecular Formula: C₁₈H₁₃NO₄S₂
• Molecular Weight: 371.438
• Mol file: 1442447-50-8.mol

Synonyms:N-methoxycarbonyl-3,4-dithiophenoylmaleimide

Chemical Property of N-methoxycarbonyl-3,4-dithiophenoylmaleimide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-methoxycarbonyl-3,4-dithiophenoylmaleimide

There total 2 articles about N-methoxycarbonyl-3,4-dithiophenoylmaleimide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

3,4-bis(phenylsulfanyl)-2,5-dihydro-1H-pyrrole-2,5-dione (32774-53-1) + methyl chloroformate (79-22-1) → N-methoxycarbonyl-3,4-dithiophenoylmaleimide (1442447-50-8)

Guidance literature:

With 4-methyl-morpholine; In ethyl acetate; at 20 ℃; for 0.5h; Cooling with ice;

Reference yield:

thiophenol (108-98-5) → N-methoxycarbonyl-3,4-dithiophenoylmaleimide (1442447-50-8)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium acetate / methanol / 0.5 h / 20 °C

2: 4-methyl-morpholine / ethyl acetate / 0.5 h / 20 °C

With 4-methyl-morpholine; sodium acetate; In methanol; ethyl acetate;

DOI:10.1016/j.tetlet.2013.04.088

Reference yield: 98.0%

N-methoxycarbonyl-3,4-dithiophenoylmaleimide (1442447-50-8) + Propargylamine (2450-71-7) → N-propargyl-2,3-bis(phenylthio)maleimide (1424958-17-7)

Guidance literature:

N-methoxycarbonyl-3,4-dithiophenoylmaleimide; Propargylamine; In dichloromethane; for 2h;

With silica gel; In dichloromethane;

DOI:10.1016/j.tetlet.2013.04.088

upstream raw materials:

3,4-bis(phenylsulfanyl)-2,5-dihydro-1H-pyrrole-2,5-dione

methyl chloroformate

thiophenol

Downstream raw materials:

N-propyl-3,4-dithiophenolmaleimide

N-propargyl-2,3-bis(phenylthio)maleimide

N-(2-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)ethyl)-3,4-dithiophenolmaleimide

N-benzyl-3,4-dithiophenolmaleimide