bis[(isobutyryloxy)methyl] 4-[2-(difluoromethoxy)phenyl]-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate

Base Information

Chemical Name:bis[(isobutyryloxy)methyl] 4-[2-(difluoromethoxy)phenyl]-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate
CAS No.:442682-38-4
Molecular Formula:C₂₆H₃₁F₂NO₉
Molecular Weight:539.53
Hs Code.:

Synonyms:bis[(isobutyryloxy)methyl] 4-[2-(difluoromethoxy)phenyl]-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate

Suppliers and Price of bis[(isobutyryloxy)methyl] 4-[2-(difluoromethoxy)phenyl]-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of bis[(isobutyryloxy)methyl] 4-[2-(difluoromethoxy)phenyl]-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of bis[(isobutyryloxy)methyl] 4-[2-(difluoromethoxy)phenyl]-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate

There total 3 articles about bis[(isobutyryloxy)methyl] 4-[2-(difluoromethoxy)phenyl]-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 71653-64-0
o-difluoromethoxybenzaldehyde

: 442682-38-4
bis[(isobutyryloxy)methyl] 4-[2-(difluoromethoxy)phenyl]-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: 38 percent / aq. NH₃ / ethanol / 6 h / Heating

2: 73 percent / KOH / ethanol / 2 h / 20 °C

3: 1.17 g / dimethylformamide / 18 h

With potassium hydroxide; ammonium hydroxide; In ethanol; N,N-dimethyl-formamide; 1: Hantzsch cyclization;
DOI:10.1016/S0957-4166(02)00022-8

Reference yield:

: 442682-35-1
bis(2-cyanoethyl) 4-[2-(difluoromethoxy)phenyl]-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate

: 442682-38-4
bis[(isobutyryloxy)methyl] 4-[2-(difluoromethoxy)phenyl]-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 73 percent / KOH / ethanol / 2 h / 20 °C

2: 1.17 g / dimethylformamide / 18 h

With potassium hydroxide; In ethanol; N,N-dimethyl-formamide;
DOI:10.1016/S0957-4166(02)00022-8