3-C-cyano-3-deoxy-1,2-O-isopropylidene-3-{[(methoxycarbonyl)methyl]amino}-5-O-trityl-α-D-ribofuranose

Base Information

• Chemical Name: 3-C-cyano-3-deoxy-1,2-O-isopropylidene-3-{[(methoxycarbonyl)methyl]amino}-5-O-trityl-α-D-ribofuranose
• CAS No.: 449205-69-0
• Molecular Formula: C₃₁H₃₂N₂O₆
• Molecular Weight: 528.605

Synonyms:3-C-cyano-3-deoxy-1,2-O-isopropylidene-3-{[(methoxycarbonyl)methyl]amino}-5-O-trityl-α-D-ribofuranose

Chemical Property of 3-C-cyano-3-deoxy-1,2-O-isopropylidene-3-{[(methoxycarbonyl)methyl]amino}-5-O-trityl-α-D-ribofuranose

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-C-cyano-3-deoxy-1,2-O-isopropylidene-3-{[(methoxycarbonyl)methyl]amino}-5-O-trityl-α-D-ribofuranose

There total 2 articles about 3-C-cyano-3-deoxy-1,2-O-isopropylidene-3-{[(methoxycarbonyl)methyl]amino}-5-O-trityl-α-D-ribofuranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

1,2-O-isopropylidene-5-O-(triphenylmethyl)-α-D-erythro-pentofuranos-3-ulose (20590-54-9) + trimethylsilyl cyanide (7677-24-9) + glycine ethyl ester hydrochloride (5680-79-5,883886-67-7) → 3-C-cyano-3-deoxy-1,2-O-isopropylidene-3-{[(methoxycarbonyl)methyl]amino}-5-O-trityl-α-D-ribofuranose (449205-69-0)

Guidance literature:

1,2-O-isopropylidene-5-O-(triphenylmethyl)-α-D-erythro-pentofuranos-3-ulose; glycine ethyl ester hydrochloride; With titanium(IV) isopropylate; TEA; In methanol;

trimethylsilyl cyanide;

DOI:10.1016/S0040-4039(02)00689-5

Reference yield: 12.0%

1,2-O-isopropylidene-5-O-(triphenylmethyl)-α-D-erythro-pentofuranos-3-ulose (20590-54-9) + trimethylsilyl cyanide (7677-24-9) + glycine ethyl ester hydrochloride (5680-79-5,883886-67-7) + titanium(IV)isopropoxide (546-68-9) → 3-C-cyano-3-deoxy-1,2-O-isopropylidene-3-{[(methoxycarbonyl)methyl]amino}-5-O-trityl-α-D-ribofuranose (449205-69-0) + ((3aR,5S,6R,6aR)-6-Cyano-2,2-dimethyl-5-trityloxymethyl-tetrahydro-furo[2,3-d][1,3]dioxol-6-ylamino)-acetic acid isopropyl ester

Guidance literature:

1,2-O-isopropylidene-5-O-(triphenylmethyl)-α-D-erythro-pentofuranos-3-ulose; glycine ethyl ester hydrochloride; titanium(IV)isopropoxide; With TEA; In methanol;

trimethylsilyl cyanide;

DOI:10.1016/S0040-4039(02)00689-5

Reference yield: 60.0%

3-C-cyano-3-deoxy-1,2-O-isopropylidene-3-{[(methoxycarbonyl)methyl]amino}-5-O-trityl-α-D-ribofuranose (449205-69-0) → (3R)-1,2-O-isopropylidene-5'-O-tritylspiro[3-deoxy-α-D-erythro-pentofuranose-3,5'-piperazine]-2'-one

Guidance literature:

With sodium tetrahydroborate; In methanol;

DOI:10.1016/S0040-4039(02)00689-5

upstream raw materials:

1,2-O-isopropylidene-5-O-(triphenylmethyl)-α-D-erythro-pentofuranos-3-ulose

trimethylsilyl cyanide

glycine ethyl ester hydrochloride

titanium(IV)isopropoxide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 449205-69-0 3-C-cyano-3-deoxy-1,2-O-isopropylidene-3-{[(methoxycarbonyl)methyl]amino}-5-O-trityl-α-D-ribofuranose

Send

Send

Metric Ton KG G Pound L ML

Send

Send