2-(5-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1H-indol-3-yl)ethanol

Base Information

Chemical Name:2-(5-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1H-indol-3-yl)ethanol
CAS No.:1262008-05-8
Molecular Formula:C₂₃H₂₄F₃NO₂
Molecular Weight:403.444
Hs Code.:

Synonyms:2-(5-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1H-indol-3-yl)ethanol

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(5-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1H-indol-3-yl)ethanol

Chemical Property:

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Technology Process of 2-(5-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1H-indol-3-yl)ethanol

There total 1 articles about 2-(5-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1H-indol-3-yl)ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 154-02-9
5-hydroxytryptophol

: 957208-65-0
4-(chloromethyl)-1-cyclopentyl-2-(trifluoromethyl)benzene

: 1262008-05-8
2-(5-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1H-indol-3-yl)ethanol

Guidance literature:: With caesium carbonate; In N,N-dimethyl-formamide; at 20 ℃;
DOI:10.1016/j.bmcl.2014.11.089

Reference yield: 56.0%

: 1262008-05-8
2-(5-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1H-indol-3-yl)ethanol

: 105-45-3
acetoacetic acid methyl ester

: C₂₇H₂₈F₃NO₄

Guidance literature:: With toluene-4-sulfonic acid; In toluene; at 80 ℃;
DOI:10.1016/j.bmcl.2014.11.089

Reference yield:

: 1262008-05-8
2-(5-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1H-indol-3-yl)ethanol

: 105-45-3
acetoacetic acid methyl ester

: 1262008-23-0
methyl 2-(6-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1-methyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetate

Guidance literature:: 2-(5-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1H-indol-3-yl)ethanol; acetoacetic acid methyl ester; toluene-4-sulfonic acid; In toluene; at 80 ℃; for 5h;

With sodium hydrogencarbonate; In toluene;