5-(tert-butyl-diphenyl-silanyloxy)-pentanoic acid methyl ester

Base Information

• Chemical Name: 5-(tert-butyl-diphenyl-silanyloxy)-pentanoic acid methyl ester
• CAS No.: 179690-97-2
• Molecular Formula: C₂₂H₃₀O₃Si
• Molecular Weight: 370.564
• Mol file: 179690-97-2.mol

Synonyms:5-(tert-butyl-diphenyl-silanyloxy)-pentanoic acid methyl ester

Chemical Property of 5-(tert-butyl-diphenyl-silanyloxy)-pentanoic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-(tert-butyl-diphenyl-silanyloxy)-pentanoic acid methyl ester

There total 19 articles about 5-(tert-butyl-diphenyl-silanyloxy)-pentanoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

methyl 5-hydroxypentanoate (14273-92-8) + tert-butylchlorodiphenylsilane (58479-61-1) → 5-(tert-butyl-diphenyl-silanyloxy)-pentanoic acid methyl ester (179690-97-2)

Guidance literature:

With 1H-imidazole; In N,N-dimethyl-formamide;

DOI:10.1016/S0040-4039(99)00579-1

Reference yield: 83.0%

tert-butyl-diphenyl-[4-(prop-2-ene-1-sulfonyl)-butoxy]-silane + methanol (67-56-1) + carbon monoxide (201230-82-2) + P-toluenesulfonyl cyanide (19158-51-1) → 5-(tert-butyl-diphenyl-silanyloxy)-pentanenitrile (845895-06-9) + 5-(tert-butyl-diphenyl-silanyloxy)-pentanoic acid methyl ester (179690-97-2)

Guidance literature:

tert-butyl-diphenyl-[4-(prop-2-ene-1-sulfonyl)-butoxy]-silane; carbon monoxide; P-toluenesulfonyl cyanide; With 1,1'-azobis(1-cyanocyclohexanenitrile); In n-heptane; at 100 ℃; under 72200 Torr;

methanol; In n-heptane; at 20 ℃;

DOI:10.1055/s-2005-921932

Reference yield: 77.0%

3-(4-(6-(tert-butyldiphenylsilyloxy)-2,2-dimethoxyhexyl)phenoxy)propyl 9,10-dioxo-9,10-dihydroanthracene-2-carboxylate (942202-94-0) → 5-(tert-butyl-diphenyl-silanyloxy)-pentanoic acid methyl ester (179690-97-2)

Guidance literature:

With sodium acetate; In water; acetonitrile; at 20 ℃; for 2.25h; Irradiation;

DOI:10.1021/ol070850k

upstream raw materials:

methyl 5-hydroxypentanoate

tert-butylchlorodiphenylsilane

methanol

carbon monoxide

Downstream raw materials:

[6-(t-butyldiphenyl-silyl)oxy]-2-oxohexylphosphonic acid dimethyl ester

5-(tert-butyl-diphenyl-silanyloxy)-pentanoic acid

(3S,4R,E)-4-benzyloxy-11-(tert-butyldiphenylsilyloxy)-3-methyl-7-oxoundec-5-enenitrile

(2S,3R,4S)-tert-butyl 3-benzyloxy-2-(6-(tert-butyldiphenylsilyloxy)-2-oxohexyl)-4-methyl-6-oxocyclohexanecarboxylate

Refernces

• 1、 Wangyang, Tu,Floreancig, Paul E.. "Intramolecular electron transfer initiated cation and radical formation through carbon-carbon bond activation". . p. 2389 - 2392. Retrieved 2008/02/05.
• 2、 Kim, Sangmo,Cho, Chang Ho,Kim, Sunggak,Uenoyama, Yoshitaka,Ryu, Ilhyong. "Radical cyanocarbonylation using alkyl allyl sulfone precursors". . p. 3160 - 3162. Retrieved 2007/10/03.