acetophenone imine hydrochloride

Base Information

• Chemical Name: acetophenone imine hydrochloride
• CAS No.: 107836-65-7
• Molecular Formula: C₈H₉N*ClH
• Molecular Weight: 155.627
• Mol file: 107836-65-7.mol

Synonyms:acetophenone imine hydrochloride

Chemical Property of acetophenone imine hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of acetophenone imine hydrochloride

There total 4 articles about acetophenone imine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

methyllithium (917-54-4) + benzonitrile (100-47-0) → acetophenone imine hydrochloride (107836-65-7)

Guidance literature:

methyllithium; benzonitrile; In tetrahydrofuran; diethyl ether; at -78 ℃; Inert atmosphere;

With methanol; In tetrahydrofuran; diethyl ether; at 20 ℃; Inert atmosphere;

With hydrogenchloride; In diethyl ether; tert-butyl methyl ether;

DOI:10.1021/ja903319r

Reference yield: 59.0%

C21H17NO (83326-64-1) → 9-fluorenone (486-25-9,952573-42-1) + acetophenone imine hydrochloride (107836-65-7)

Guidance literature:

With hydrogenchloride; potassium tert-butylate; In dimethyl sulfoxide; for 15h; Ambient temperature;

Reference yield:

acetophenone (98-86-2) → acetophenone imine hydrochloride (107836-65-7)

Guidance literature:

With titanium(IV) isopropylate; ammonia; titanium tetrachloride; In diethyl ether; pentane; at 0 ℃; for 1h;

DOI:10.3891/acta.chem.scand.51-0351

upstream raw materials:

C₂₁H₁₇NO

acetophenone

N-1-Phenylethylfluorenimin

methyllithium

Downstream raw materials:

2-phenyl-Δ²-pyrroline-4,5-dione

rac-methylbenzylamine

(R)-1-phenylethylamine hydrochloride

(S)-(-)-α-methylbenzylamine hydrochloride