DiMethyl 3-(benzyloxy)-1-(2,2-diMethoxyethyl)-4-oxo-1,4-dihydropyridine-2,5-dicarboxylate

Base Information

Chemical Name:DiMethyl 3-(benzyloxy)-1-(2,2-diMethoxyethyl)-4-oxo-1,4-dihydropyridine-2,5-dicarboxylate
CAS No.:1357289-08-7
Molecular Formula:C₂₀H₂₃NO₈
Molecular Weight:405.405
Hs Code.:
Mol file:1357289-08-7.mol

Synonyms:2,5-dimethyl 3-(benzyloxy)-1-(2,2-dimethoxyethyl)-4-oxo-1,4-dihydropyridine-2,5-dicarboxylate

Suppliers and Price of DiMethyl 3-(benzyloxy)-1-(2,2-diMethoxyethyl)-4-oxo-1,4-dihydropyridine-2,5-dicarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Dimethyl3-(benzyloxy)-1-(2,2-dimethoxyethyl)-4-oxo-1,4-dihydropyridine-2,5-dicarboxylate 97%
1g
$ 653.00

Total 36 raw suppliers

Chemical Property of DiMethyl 3-(benzyloxy)-1-(2,2-diMethoxyethyl)-4-oxo-1,4-dihydropyridine-2,5-dicarboxylate

Chemical Property:

Boiling Point:557.8±50.0 °C(Predicted)
PKA:-1.29±0.10(Predicted)
Density:1.28±0.1 g/cm3(Predicted)

Purity/Quality:

99%, ^*data from raw suppliers

Dimethyl3-(benzyloxy)-1-(2,2-dimethoxyethyl)-4-oxo-1,4-dihydropyridine-2,5-dicarboxylate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of DiMethyl 3-(benzyloxy)-1-(2,2-diMethoxyethyl)-4-oxo-1,4-dihydropyridine-2,5-dicarboxylate

There total 6 articles about DiMethyl 3-(benzyloxy)-1-(2,2-diMethoxyethyl)-4-oxo-1,4-dihydropyridine-2,5-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 1246616-66-9
dimethyl 3-(benzyloxy)-4-oxo-4H-pyran-2,5-dicarboxylate

: 22483-09-6
2,2-dimethoxyethylamine

: 1357289-08-7
2,5-dimethyl 3-(benzyloxy)-1-(2,2-dimethoxyethyl)-4-oxo-1,4-dihydropyridine-2,5-dicarboxylate

Guidance literature:: In toluene; at 100 ℃; for 3h;

Reference yield:

: 67354-34-1
ethyl 4-benzyloxyacetoacetate

: 124-41-4
sodium methylate

: 22483-09-6
2,2-dimethoxyethylamine

: 1357289-08-7
2,5-dimethyl 3-(benzyloxy)-1-(2,2-dimethoxyethyl)-4-oxo-1,4-dihydropyridine-2,5-dicarboxylate

Guidance literature:: ethyl 4-benzyloxyacetoacetate; With N,N-dimethyl-formamide dimethyl acetal; In toluene; at 20 - 30 ℃; for 1h;

2,2-dimethoxyethylamine; In toluene; at 20 - 30 ℃; for 1h;

sodium methylate; With Dimethyl oxalate; In methanol; at 5 - 45 ℃; for 20h;

Reference yield:

: 82961-76-0
4-benzyloxy-3-oxobutyric acid methyl ester

: 1357289-08-7
2,5-dimethyl 3-(benzyloxy)-1-(2,2-dimethoxyethyl)-4-oxo-1,4-dihydropyridine-2,5-dicarboxylate

Guidance literature:: Multi-step reaction with 3 steps

1.1: 1,4-dioxane / 6 h / 20 °C

2.1: sodium t-butanolate / 7 h / 25 - 30 °C / Inert atmosphere

2.2: 15 h / 20 °C

3.1: methanol / 6 h / Reflux

With sodium t-butanolate; In 1,4-dioxane; methanol;