N'-methyl-N'-phenylformohydrazide

Base Information

• Chemical Name: N'-methyl-N'-phenylformohydrazide
• CAS No.: 38604-67-0
• Molecular Formula: C₈H₁₀N₂O
• Molecular Weight: 150.18
• Mol file: 38604-67-0.mol

Synonyms:N'-methyl-N'-phenylformohydrazide

Chemical Property of N'-methyl-N'-phenylformohydrazide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N'-methyl-N'-phenylformohydrazide

There total 3 articles about N'-methyl-N'-phenylformohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-Methyl-1-phenylhydrazine (618-40-6) + formic acid ethyl ester (109-94-4) → N'-methyl-N'-phenylformohydrazide (38604-67-0)

Guidance literature:

DOI:10.1016/S0040-4039(97)00320-1

Reference yield:

N-methylaniline (100-61-8) → N'-methyl-N'-phenylformohydrazide (38604-67-0)

Guidance literature:

Multi-step reaction with 3 steps

1: hydrogenchloride; sodium nitrite / water; ethyl acetate / 20 °C / Cooling with ice

2: lithium aluminium tetrahydride / diethyl ether / 20 °C / Cooling with ice

3: 72 h / 20 °C

With hydrogenchloride; lithium aluminium tetrahydride; sodium nitrite; In diethyl ether; water; ethyl acetate;

DOI:10.1016/j.tetlet.2018.08.025

Reference yield:

N-methyl-N-nitrosoaniline (614-00-6) → N'-methyl-N'-phenylformohydrazide (38604-67-0)

Guidance literature:

Multi-step reaction with 2 steps

1: lithium aluminium tetrahydride / diethyl ether / 20 °C / Cooling with ice

2: 72 h / 20 °C

With lithium aluminium tetrahydride; In diethyl ether;

DOI:10.1016/j.tetlet.2018.08.025

upstream raw materials:

1-Methyl-1-phenylhydrazine

formic acid ethyl ester

N-methylaniline

N-methyl-N-nitrosoaniline

Downstream raw materials:

C₈H₈N₂

N,N,N'-trimethyl-N'-phenylhydrazine

benzoic acid N,N'-dimethyl-N'-phenylhydrazide

N'-methyl-N-methyl-N-phenylhydrazine