Methyl 2-(2-(benzyloxy)phenyl)acetate

Base Information

• Chemical Name: Methyl 2-(2-(benzyloxy)phenyl)acetate
• CAS No.: 40525-65-3
• Molecular Formula: C16H16 O3
• Molecular Weight: 256.301
• Hs Code.: 2918990090
• DSSTox Substance ID: DTXSID90454376
• Nikkaji Number: J1.135.642G
• Wikidata: Q82275867
• Mol file: 40525-65-3.mol

Synonyms:Methyl 2-(2-(benzyloxy)phenyl)acetate;40525-65-3;Methyl 2-(phenylmethoxy)-benzeneacetate;Methyl 2-(2-phenylmethoxyphenyl)acetate;methyl 2-(phenylmethoxy)benzeneacetate;methyl 2-benzyloxyphenylacetate;SCHEMBL2988197;DTXSID90454376;methyl (2-benzyloxyphenyl)acetate;CPIKEDMPXDEUED-UHFFFAOYSA-N;Methyl 2-(benzyloxy)-phenylacetate;Methyl [2-(benzyloxy)phenyl]acetate;AKOS015960771;AB16613;DS-7036;2-benzyloxyphenylacetic acid methyl ester;AC-12342;2-(Benzyloxy)phenylacetic acid methyl ester;CS-0197209;FT-0758467;O11845

Chemical Property of Methyl 2-(2-(benzyloxy)phenyl)acetate

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.56
• Boiling Point: 364.8°Cat760mmHg
• Flash Point: 152.5°C
• PSA: 35.53000
• Density: 1.129g/cm³
• LogP: 2.98110
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 2.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 6
• Exact Mass: 256.109944368
• Heavy Atom Count: 19
• Complexity: 271

Purity/Quality:

98%min ^*data from raw suppliers

Methyl2-(2-(Benzyloxy)phenyl)acetate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: COC(=O)CC1=CC=CC=C1OCC2=CC=CC=C2

Technology Process of Methyl 2-(2-(benzyloxy)phenyl)acetate

There total 15 articles about Methyl 2-(2-(benzyloxy)phenyl)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methyl (2-hydroxyphenyl)acetate (22446-37-3) + benzyl bromide (100-39-0) → 2-benzyloxyphenylacetic acid methyl ester (40525-65-3)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 10h;

Reference yield: 90.0%

methanol (67-56-1) + 1-Benzyloxy-2-((E)-2-ethanesulfinyl-2-ethylsulfanyl-vinyl)-benzene → 2-benzyloxyphenylacetic acid methyl ester (40525-65-3)

Guidance literature:

With hydrogenchloride; Heating;

DOI:10.1080/00397919908086239

Reference yield: 83.0%

methyl (2-hydroxyphenyl)acetate (22446-37-3) + benzyl bromide (100-39-0) → (E)-methyl 2-[2'-(5-nitropyridin-2-yloxy)phenyl]-3-methoxyacrylate (114077-60-0) + 2-benzyloxyphenylacetic acid methyl ester (40525-65-3)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide;

upstream raw materials:

methanol

2-hydroxyphenylacetic acid benzyl ether

cyclohexanone

salicylic alcohol

Downstream raw materials:

2-(2-benzyloxy-phenyl)-3-(4-methoxy-benzo[1,3]dioxol-5-yl)-3-oxo-propionic acid methyl ester

dimethyl 2-[2-(benzyloxy)benzyl]malonate

2,2-dimethyl-propionic acid 3-hydroxy-2-(2-hydroxy-phenyl)-propyl ester

2-[2-(benzyloxy)phenyl]-1,3-propanediol