t-butyl (S)-2-chloro-6-[1-(4-fluorophenyl)ethylamino]pyridin-4-yl-carbamate

Base Information

Chemical Name:t-butyl (S)-2-chloro-6-[1-(4-fluorophenyl)ethylamino]pyridin-4-yl-carbamate
CAS No.:1239363-32-6
Molecular Formula:C₁₈H₂₁ClFN₃O₂
Molecular Weight:365.835
Hs Code.:

Synonyms:t-butyl (S)-2-chloro-6-[1-(4-fluorophenyl)ethylamino]pyridin-4-yl-carbamate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of t-butyl (S)-2-chloro-6-[1-(4-fluorophenyl)ethylamino]pyridin-4-yl-carbamate

Chemical Property:

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Technology Process of t-butyl (S)-2-chloro-6-[1-(4-fluorophenyl)ethylamino]pyridin-4-yl-carbamate

There total 2 articles about t-butyl (S)-2-chloro-6-[1-(4-fluorophenyl)ethylamino]pyridin-4-yl-carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5398-44-7
2,6-dichloropyridine-4-carboxylic acid

: 1239363-32-6
t-butyl (S)-2-chloro-6-[1-(4-fluorophenyl)ethylamino]pyridin-4-yl-carbamate

Guidance literature:: Multi-step reaction with 2 steps

1: diphenylphosphoranyl azide; triethylamine / Reflux

2: sodium t-butanolate / palladium diacetate / 1,4-dioxane / 10 h / 100 °C / Inert atmosphere

With diphenylphosphoranyl azide; triethylamine; sodium t-butanolate; palladium diacetate; In 1,4-dioxane;

Reference yield:

: 501907-61-5
tert-butyl (2,6-dichloropyridin-4-yl)carbamate

: 66399-30-2
(S)-1-(4-Fluoro-phenyl)-ethylamine

: 1239363-32-6
t-butyl (S)-2-chloro-6-[1-(4-fluorophenyl)ethylamino]pyridin-4-yl-carbamate

Guidance literature:: With sodium t-butanolate; palladium diacetate; In 1,4-dioxane; at 100 ℃; for 10h; Inert atmosphere;

Reference yield:

: 5049-61-6
2-Aminopyrazine

: 1239363-32-6
t-butyl (S)-2-chloro-6-[1-(4-fluorophenyl)ethylamino]pyridin-4-yl-carbamate

: 1239363-33-7
t-butyl (S)-2-[1-(4-fluorophenyl)ethylamino]-6-(pyrazin-2-ylamino)pyridin-4-yl-carbamate

Guidance literature:: With sodium t-butanolate; XPhos; tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; In toluene; at 100 ℃; Inert atmosphere;