501907-61-5

Usage

Uses

Used in Agricultural Industry:
Carbamic acid, (2,6-dichloro-4-pyridinyl)-, 1,1-dimethylethyl ester (9CI) is used as an insecticide and acaricide for controlling pests in various crops such as cotton, vegetables, and fruit trees. It is effective against a wide range of insects and mites, ensuring the protection and yield of these crops.
Used in Residential and Commercial Settings:
In residential and commercial settings, Carbamic acid, (2,6-dichloro-4-pyridinyl)-, 1,1-dimethylethyl ester (9CI) is used as a pest control agent to manage and eliminate infestations of insects and mites. Its application helps maintain a clean and healthy environment by reducing the presence of pests that can cause damage or transmit diseases.

Upstream product

• 5398-44-7 2,6-dichloropyridine-4-carboxylic acid 
• 75-65-0 tert-butyl alcohol 

Downstream Products

• 929288-17-5 4-(tert-butoxycarbonylamino)-2,6-dichloronicotinic acid 
• 1239363-32-6 t-butyl (S)-2-chloro-6-[1-(4-fluorophenyl)ethylamino]pyridin-4-yl-carbamate 
• 1239362-50-5 (S)-N-{2-[1-(4-fluorophenyl)indolylethylamino]-6-(aminopyrazine-2-ylamino)-4-yl}aminoacetamide 
• 1239362-55-0 (S)-1-{2-[1-(4-fluorophenyl)indolylethylamino]-6-(aminopyrazine-2-ylamino)-4-yl}pyrazolesulfonylurea 
• 1239363-34-8 (S)-N₂-[1-(4-fluorophenyl)ethyl]-N₆-(pyrazin-2-yl)pyridine-2,4,6-triamine 
• 1239363-33-7 t-butyl (S)-2-[1-(4-fluorophenyl)ethylamino]-6-(pyrazin-2-ylamino)pyridin-4-yl-carbamate 
• 2587-02-2 2,6-dichloro-[4]pyridylamine 
• 914942-86-2 2,6-dichloro-4-N-methylpyridine-3,4-diamine 
• 887147-20-8 2,6-dichloro-N-methyl-3-nitro pyridine-4-amine 

Relevant academic research and scientific papers

Preparation method of 4-amino-2,6-dichloropyridine

The invention relates to a preparation method of a halogen-substituted pyridylamine compound, particularly to a preparation method of 4-amino-2,6-dichloropyridine, wherein 2,6-dihydroxy isonicotinic acid is used as a raw material and is subjected to chlorination reaction, Curtius rearrangement or further amine protection group removal to obtain the product. The method has the advantages of accessible raw materials, high yield and low impurity content, avoids the use of explosive reagent sodium azide, and can be further applied to industrial production.

BICYCLIC INHIBITORS OF ALK

The present invention relates to compounds of formula (1) or pharmaceutical acceptable salts, Formula (1) wherein R1, R2, R3, X, Y, Z, A, B, G1, m, and n are defined in the description. The present invention relates also to compositions containing said compounds which are useful for inhibiting kinases such as ALK and methods of treating diseases such as cancer.

BICYCLIC INHIBITORS OF ALK

The present invention relates to compounds of formula (1) or pharmaceutical acceptable salts, wherein R1, X, Y, Z, A, B, G1, and n are defined in the description. The present invention relates also to compositions containing said compounds which are useful for inhibiting kinases such as ALK and methods of treating diseases such as cancer.

BICYCLIC INHIBITORS OF ANAPHASTIC LYMPHOMA KINASE

Disclosed are compounds of formula (Ⅰ) and their pharmaceutical acceptable salts, wherein R1, R2, R3, X, Y, Z, A, B, G1, m and n are defined in the description. The compositions containing the said compounds used for inhibiting kinases such as anaphastic lymphoma kinase (ALK) and methods of treating diseases such as cancer are disclosed.

BICYCLIC INHIBITORS OF ALK

The present invention relates to compounds of formula (1) or pharmaceutical acceptable salts, Formula (1) wherein R1, R2, R3, X, Y, Z, A, B, G1, m, and n are defined in the description. The present invention relates also to compositions containing said compounds which are useful for inhibiting kinases such as ALK and methods of treating diseases such as cancer.

AMINOPYRAZINE DERIVATIVE AND MEDICINE

The present invention relates to a compound represented by general formula [1] satisfying the following (I) or (II), or a pharmaceutical acceptable salt of the compound. (I) X is CH or N; R1 is a halogen atom,; and R2 is H, a halogen atom, CN, [2], [3], [8], [9], an —O-alkyl, an —O-(saturated ring), etc. [2]: —C(RC)(RD)(RE) (RC to RE each are H, an alkyl, etc.) [3]: —N(RF)(RG) (RF and RG each are H, OH, amino, a (hetero)aryl, etc.) [8]: —C(═O)RL (RL is an alkyl, OH, an alkoxy, amino, etc.) [9]: a (substituted)phenyl; (II) X is >C—C(—O)R3 (R3 is a (substituted)amino, an alkoxy, OH, etc.); R1 is a halogen atom; R2 is H; R3 is H or OH; and R3 and R4 each are H or an alkyl.