1-(4-Hydroxyphenyl)-3-Methylurea

Base Information

• Chemical Name: 1-(4-Hydroxyphenyl)-3-Methylurea
• CAS No.: 38652-14-1
• Molecular Formula: C8H10 N2 O2
• Molecular Weight: 166.18
• Hs Code.: 2924299090
• Mol file: 38652-14-1.mol

Synonyms:Urea,1-(p-hydroxyphenyl)-3-methyl- (7CI); 1-(4-Hydroxyphenyl)-3-methylurea;1-(p-Hydroxyphenyl)-3-methylurea; N-(4-Hydroxyphenyl)-N'-methylurea; NSC 409428

Chemical Property of 1-(4-Hydroxyphenyl)-3-Methylurea

Chemical Property:

• Vapor Pressure: 0.000596mmHg at 25°C
• Boiling Point: 301.3°Cat760mmHg
• Flash Point: 136°C
• PSA: 61.36000
• Density: 1.28g/cm³
• LogP: 1.60740
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

1-(4-Hydroxyphenyl)-3-methylurea 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-(4-Hydroxyphenyl)-3-Methylurea

There total 5 articles about 1-(4-Hydroxyphenyl)-3-Methylurea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

monuron (150-68-5) → C9H11ClN2O2 + 1-(4-hydroxyphenyl)-3-methylurea (38652-14-1) + 3-(4-hydroxyphenyl)-1,1-dimethylurea (2908-80-7) + C10H11NO2 + 3-(4-chloro-2-nitrophenyl)-1,1-dimethylurea (1086694-75-8) + 3-(4-chlorophenyl)-1-methylurea (5352-88-5) + 3-(4-Chlor-2-hydroxyphenyl)-1-methylharnstoff (28443-46-1) + 3-(4-Hydroxyphenyl)-1-formyl-1-methylharnstoff (63297-41-6) + N1N1-dimethyl-N2-(2-hydroxy-4-chlorophenyl) urea (25546-09-2) + N'-(4-chloro-phenyl)-N-formyl-N-methyl-urea (25546-06-9)

Guidance literature:

With potassium nitrate; In water; for 10h; Concentration; pH-value; Wavelength; Reagent/catalyst; Time; Kinetics; Irradiation at 310 nm;

DOI:10.1039/c2pp25044f

Reference yield:

4-amino-phenol (123-30-8) + methyl isocyanate (624-83-9) → 1-(4-hydroxyphenyl)-3-methylurea (38652-14-1)

Guidance literature:

In chloroform;

DOI:10.1021/jm00342a010

Reference yield:

p-aminophenol hydrochloride (51-78-5) + methyl isocyanate (624-83-9) → 1-(4-hydroxyphenyl)-3-methylurea (38652-14-1)

Guidance literature:

With sodium carbonate;

upstream raw materials:

4-amino-phenol

methyl isocyanate

p-aminophenol hydrochloride

monuron

Downstream raw materials:

1-[4-(3-tert-Butylamino-2-hydroxy-propoxy)-phenyl]-3-methyl-urea

1-(4-{3-[2-(3,4-Dimethoxy-phenyl)-ethylamino]-2-hydroxy-propoxy}-phenyl)-3-methyl-urea

4-(2-{2-Hydroxy-3-[4-(3-methyl-ureido)-phenoxy]-propylamino}-ethoxy)-benzamide