2-methyl-5-oxohexanal

Base Information

• Chemical Name: 2-methyl-5-oxohexanal
• CAS No.: 59333-74-3
• Molecular Formula: C₇H₁₂O₂
• Molecular Weight: 128.171
• Mol file: 59333-74-3.mol

Synonyms:2-methyl-5-oxohexanal

Chemical Property of 2-methyl-5-oxohexanal

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 2-methyl-5-oxohexanal

There total 1 articles about 2-methyl-5-oxohexanal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methanol (67-56-1) + 5-Hexen-2-one (109-49-9) + carbon monoxide (201230-82-2) → 6-oxoheptanal (19480-04-7) + n-hexan-2-one (591-78-6) + 2-methyl-5-oxohexanal (59333-74-3) + C9H18O3 + 2-oxoheptanal dimethylacetal (36727-64-7)

Guidance literature:

With bis(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate; hydrogen; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; at 110 ℃; for 1h; under 22502.3 Torr; regioselective reaction; Autoclave;

DOI:10.1002/adsc.201100707

Reference yield:

2-methyl-5-oxohexanal (59333-74-3) → (+)-(R)-4-methyl-2-cyclohexene-1-one (75337-05-2) + (S)-(-)-4-methyl-2-cyclohexen-1-one (101758-35-4)

Guidance literature:

With (S)-2-(pyrrolidinomethyl)pyrrolidine trifluoroacetate; In hexane; Overall yield = 82 %;

DOI:10.1021/ol301874x

upstream raw materials:

methanol

5-Hexen-2-one

carbon monoxide

Downstream raw materials:

(+)-(R)-4-methyl-2-cyclohexene-1-one

(S)-(-)-4-methyl-2-cyclohexen-1-one