4-(2-nitro phenylthio)benzylacetate

Base Information

• Chemical Name: 4-(2-nitro phenylthio)benzylacetate
• CAS No.: 126585-12-4
• Molecular Formula: C₁₅H₁₃NO₄S
• Molecular Weight: 303.339
• Mol file: 126585-12-4.mol

Synonyms:4-(2-nitro phenylthio)benzylacetate

Chemical Property of 4-(2-nitro phenylthio)benzylacetate

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 4-(2-nitro phenylthio)benzylacetate

There total 6 articles about 4-(2-nitro phenylthio)benzylacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

acetyl chloride (75-36-5) + 4-(2-nitro phenylthio)benzyl alcohol (126585-10-2) → 4-(2-nitro phenylthio)benzylacetate (126585-12-4)

Guidance literature:

With triethylamine; In benzene; for 0.5h; Ambient temperature;

Reference yield: 71.0%

acetic acid (64-19-7,77671-22-8) + C13H10BrNO2S (126616-89-5) → 4-(2-nitro phenylthio)benzylacetate (126585-12-4)

Guidance literature:

With sodium acetate; for 15h; Heating;

Reference yield:

2-(4-methylphenylsulfanyl)nitrobenzene (20912-17-8) → 4-(2-nitro phenylthio)benzylacetate (126585-12-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 1.) NBS, benzoyl-peroxide; 2.) silver nitrate / 1.) CCl₄, reflux, 15 h; 2.) acetone, water, room temp., 1 h

2: 70 percent / NaBH₄ / ethanol / 1 h / Ambient temperature

3: 73 percent / Et₃N / benzene / 0.5 h / Ambient temperature

With sodium tetrahydroborate; N-Bromosuccinimide; Perbenzoic acid; silver nitrate; triethylamine; In ethanol; benzene;

upstream raw materials:

acetic acid

C₁₃H₁₀BrNO₂S

acetyl chloride

4-(2-nitro phenylthio)benzyl alcohol

Downstream raw materials:

Acetic acid 4-[2-(2-diethylamino-acetylamino)-phenylsulfanyl]-benzyl ester

Acetic acid 4-[2-(4-chloro-benzoylamino)-phenylsulfanyl]-benzyl ester

Acetic acid 4-[2-(2-chloro-acetylamino)-phenylsulfanyl]-benzyl ester

Acetic acid 4-(2-amino-phenylsulfanyl)-benzyl ester

Refernces