2-(4-{[3-(2,4-difluorophenyl)-3-oxopropanimidoyl]-amino}phenyl)ethyl acetate

Base Information

Chemical Name:2-(4-{[3-(2,4-difluorophenyl)-3-oxopropanimidoyl]-amino}phenyl)ethyl acetate
CAS No.:1151805-27-4
Molecular Formula:C₁₉H₁₈F₂N₂O₃
Molecular Weight:360.36
Hs Code.:

Synonyms:2-(4-{[3-(2,4-difluorophenyl)-3-oxopropanimidoyl]-amino}phenyl)ethyl acetate

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Chemical Property of 2-(4-{[3-(2,4-difluorophenyl)-3-oxopropanimidoyl]-amino}phenyl)ethyl acetate

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Technology Process of 2-(4-{[3-(2,4-difluorophenyl)-3-oxopropanimidoyl]-amino}phenyl)ethyl acetate

There total 2 articles about 2-(4-{[3-(2,4-difluorophenyl)-3-oxopropanimidoyl]-amino}phenyl)ethyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 764645-61-6
4-chlorophenyl 3-(2,4-difluorophenyl)-3-oxo-propanimidothioate

: 104-10-9
2-(4'-aminophenyl)ethyl alcohol

: 1151805-27-4
2-(4-{[3-(2,4-difluorophenyl)-3-oxopropanimidoyl]-amino}phenyl)ethyl acetate

Guidance literature:: 4-chlorophenyl 3-(2,4-difluorophenyl)-3-oxo-propanimidothioate; 2-(4'-aminophenyl)ethyl alcohol; With acetic acid; at 80 ℃; for 2.5h;

With sodium hydrogencarbonate; for 0.5h;

Reference yield: 92.0%

: 764645-61-6
4-chlorophenyl 3-(2,4-difluorophenyl)-3-oxo-propanimidothioate

: 64-19-7,77671-22-8
acetic acid

: 104-10-9
2-(4'-aminophenyl)ethyl alcohol

: 1151805-27-4
2-(4-{[3-(2,4-difluorophenyl)-3-oxopropanimidoyl]-amino}phenyl)ethyl acetate

Guidance literature:: 4-chlorophenyl 3-(2,4-difluorophenyl)-3-oxo-propanimidothioate; acetic acid; 2-(4'-aminophenyl)ethyl alcohol; at 80 ℃; for 2.5h;

With sodium hydrogencarbonate; In diethyl ether; water; for 0.5h;

Reference yield: 64.0%

: 1151805-27-4
2-(4-{[3-(2,4-difluorophenyl)-3-oxopropanimidoyl]-amino}phenyl)ethyl acetate

: 471-25-0
Propiolic acid

: 1151805-29-6
2-{4-[6-amino-5-(2,4-difluorobenzoyl)-2-oxopyridin-1(2H)-yl]phenyl}ethyl acetate

Guidance literature:: Propiolic acid; With 1,1'-carbonyldiimidazole; In tetrahydrofuran; at 0 - 20 ℃; for 1h;

2-(4-{[3-(2,4-difluorophenyl)-3-oxopropanimidoyl]-amino}phenyl)ethyl acetate; In tetrahydrofuran; at 80 ℃; for 6h;