1-Methoxy-4-(1-phenylethyl)benzene

Base Information

• Chemical Name: 1-Methoxy-4-(1-phenylethyl)benzene
• CAS No.: 2605-18-7
• Molecular Formula: C15H16O
• Molecular Weight: 212.291
• Hs Code.: 2909309090
• NSC Number: 163360
• DSSTox Substance ID: DTXSID30303899
• Nikkaji Number: J899.674A
• Mol file: 2605-18-7.mol

Synonyms:1-methoxy-4-(1-phenylethyl)benzene;2605-18-7;1-METHOXY-4-(1-PHENYL-ETHYL)-BENZENE;Benzene, 1-methoxy-4-(1-phenylethyl)-;NSC163360;SCHEMBL156425;DTXSID30303899;AKOS015967061;NSC-163360;CS-0435438;FT-0702529;F74835

Chemical Property of 1-Methoxy-4-(1-phenylethyl)benzene

Chemical Property:

• Vapor Pressure: 0.00104mmHg at 25°C
• Melting Point: 75-76 °C
• Refractive Index: 1.549
• Boiling Point: 311.249 °C at 760 mmHg
• Flash Point: 121.705 °C
• PSA: 9.23000
• Density: 1.01 g/cm³
• LogP: 3.84700
• XLogP3: 4.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 212.120115130
• Heavy Atom Count: 16
• Complexity: 188

Purity/Quality:

99% ^*data from raw suppliers

1-METHOXY-4-(1-PHENYL-ETHYL)-BENZENE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C1=CC=CC=C1)C2=CC=C(C=C2)OC

Technology Process of 1-Methoxy-4-(1-phenylethyl)benzene

There total 68 articles about 1-Methoxy-4-(1-phenylethyl)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

1-(4-methoxyphenyl)-1-phenylethene (4333-75-9) → 1-methoxy-4-(1-phenylethyl)benzene (2605-18-7)

Guidance literature:

With boron trifluoride diethyl etherate; (1,4-dihydro-[1,1'-biphenyl]-3-yl)trimethylsilane; In dichloromethane; at 20 ℃; for 12h; regioselective reaction;

DOI:10.1021/acs.orglett.0c00213

Reference yield: 98.0%

(1-bromoethyl)benzne (585-71-7,38661-81-3) + 4-methoxyphenyl magnesium bromide (13139-86-1) → 1-methoxy-4-(1-phenylethyl)benzene (2605-18-7)

Guidance literature:

With dichloro bis(acetonitrile) palladium(II); 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In tetrahydrofuran; at 20 ℃; for 14h; Inert atmosphere;

DOI:10.1021/ol902335c

Reference yield: 96.0%

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + methoxybenzene (100-66-3) → 1-methoxy-4-(1-phenylethyl)benzene (2605-18-7)

Guidance literature:

With H-β-zeolite; In cyclohexane; at 80 ℃; for 6h;

DOI:10.1002/ejoc.201200283

upstream raw materials:

1-(4-methoxyphenyl)-1-phenylethene

di-tert-butyl peroxide

3-(4-methoxyphenyl)-3-phenylpropanal

1-(4-hydroxyphenyl)-1-phenylethane

Downstream raw materials:

C₁₅H₁₆O₃

1-(4-methoxyphenyl)-1-phenylethan-1-ol

4-Methoxybenzophenone

(E)-1-methoxy-4-(2-nitro-1-phenylethenyl)benzene