2-thiophenecarboxylic methylester 3-N-[(2,4-dimethyl-phenyl)-phosphonamidate methyl ester]-5-(4-fluorophenyl)

Base Information

Chemical Name:2-thiophenecarboxylic methylester 3-N-[(2,4-dimethyl-phenyl)-phosphonamidate methyl ester]-5-(4-fluorophenyl)
CAS No.:1243141-22-1
Molecular Formula:C₂₁H₂₁FNO₄PS
Molecular Weight:433.44
Hs Code.:

Synonyms:2-thiophenecarboxylic methylester 3-N-[(2,4-dimethyl-phenyl)-phosphonamidate methyl ester]-5-(4-fluorophenyl)

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Chemical Property of 2-thiophenecarboxylic methylester 3-N-[(2,4-dimethyl-phenyl)-phosphonamidate methyl ester]-5-(4-fluorophenyl)

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Technology Process of 2-thiophenecarboxylic methylester 3-N-[(2,4-dimethyl-phenyl)-phosphonamidate methyl ester]-5-(4-fluorophenyl)

There total 1 articles about 2-thiophenecarboxylic methylester 3-N-[(2,4-dimethyl-phenyl)-phosphonamidate methyl ester]-5-(4-fluorophenyl) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 31.0%

: 1198089-62-1
(2,4-dimethyl-phenyl)-phosphonic acid methyl ester

: 175137-08-3
5-(4-fluorophenyl)-3-aminothiophene-2-carboxylic acid methyl ester

: 1243141-22-1
2-thiophenecarboxylic methylester 3-N-[(2,4-dimethyl-phenyl)-phosphonamidate methyl ester]-5-(4-fluorophenyl)

Guidance literature:: (2,4-dimethyl-phenyl)-phosphonic acid methyl ester; With thionyl chloride; N,N-dimethyl-formamide; In dichloromethane; at 20 ℃; Inert atmosphere;

5-(4-fluorophenyl)-3-aminothiophene-2-carboxylic acid methyl ester; With pyridine; sodium hydride; In tetrahydrofuran; mineral oil; at 20 ℃;

Reference yield:

: 1243141-22-1
2-thiophenecarboxylic methylester 3-N-[(2,4-dimethyl-phenyl)-phosphonamidate methyl ester]-5-(4-fluorophenyl)

: 75-26-3
isopropyl bromide

: 1243141-97-0
2-thiophenecarboxylic methylester 3-N-methyl-N-[(2,4-dimethyl-phenyl)-phosphonamidate methyl ester]-5-(4-fluorophenyl)

Guidance literature:: 2-thiophenecarboxylic methylester 3-N-[(2,4-dimethyl-phenyl)-phosphonamidate methyl ester]-5-(4-fluorophenyl); With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 20 ℃; for 0.0833333h; Inert atmosphere;

isopropyl bromide; In N,N-dimethyl-formamide; mineral oil; at 60 ℃;