4-Methoxy-alpha-(2-methylphenyl)benzenemethanol

Base Information

Chemical Name:4-Methoxy-alpha-(2-methylphenyl)benzenemethanol
CAS No.:220583-41-5
Molecular Formula:C₁₅H₁₆O₂
Molecular Weight:228.291
Hs Code.:
DSSTox Substance ID:DTXSID501264222
Nikkaji Number:J3.498.667C

Synonyms:DTXSID501264222;AKOS010016145;J3.498.667C;4-Methoxy-alpha-(2-methylphenyl)benzenemethanol;alpha-(2-Methylphenyl)-4-methoxybenzyl alcohol;220583-41-5

Suppliers and Price of 4-Methoxy-alpha-(2-methylphenyl)benzenemethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-Methoxy-alpha-(2-methylphenyl)benzenemethanol

Chemical Property:

XLogP3:3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:228.115029749
Heavy Atom Count:17
Complexity:221

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC=CC=C1C(C2=CC=C(C=C2)OC)O

Technology Process of 4-Methoxy-alpha-(2-methylphenyl)benzenemethanol

There total 5 articles about 4-Methoxy-alpha-(2-methylphenyl)benzenemethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 16419-60-6
2-Methylphenylboronic acid

: 123-11-5
4-methoxy-benzaldehyde

: 220583-41-5
4-methoxyphenyl(2-methylphenyl)methanol

Guidance literature:: With tri-tert-butyl phosphine; {rhodium(acetylacetonate)(cis-cyclooctene)2}; In 1,2-dimethoxyethane; water; at 25 - 28 ℃; for 16h;
DOI:10.1021/jo000187c

Reference yield: 79.0%

: 104-92-7
1-bromo-4-methoxy-benzene

: 529-20-4
2-methylphenyl aldehyde

: 220583-41-5
4-methoxyphenyl(2-methylphenyl)methanol

Guidance literature:: With nickel(II) bromide 2-methoxyethyl ether complex; 4,4'-di-tert-butyl-2,2'-bipyridine; zinc; In tetrahydrofuran; at 60 ℃; for 16h; Sealed tube; Inert atmosphere;
DOI:10.1021/jacs.8b13709

Reference yield:

: C₁₉H₂₃NO₂S

: 19226-36-9
3-phenyl-5H-1,4,2-dioxazol-5-one

: C₂₂H₁₈N₂O

: 220583-41-5
4-methoxyphenyl(2-methylphenyl)methanol

Guidance literature:: C₁₉H₂₃NO₂S; 3-phenyl-5H-1,4,2-dioxazol-5-one; With carbonyl(pentamethylcyclopentadienyl)cobalt diiodide; silver(I) triflimide; In 1,2-dichloro-ethane; at 120 ℃; for 16h; Inert atmosphere; Sealed tube;

With sodium tetrahydroborate; In methanol; at 20 ℃; for 0.5h; Inert atmosphere; Sealed tube;
DOI:10.1021/acs.orglett.6b00227