1-methyl-3-(2-methylsulfanyl-benzyl)-3H-imidazol-1-ium; bromide

Base Information

• Chemical Name: 1-methyl-3-(2-methylsulfanyl-benzyl)-3H-imidazol-1-ium; bromide
• CAS No.: 914402-05-4
• Molecular Formula: Br*C₁₂H₁₅N₂S
• Molecular Weight: 299.235
• Mol file: 914402-05-4.mol

Synonyms:1-methyl-3-(2-methylsulfanyl-benzyl)-3H-imidazol-1-ium; bromide

Chemical Property of 1-methyl-3-(2-methylsulfanyl-benzyl)-3H-imidazol-1-ium; bromide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-methyl-3-(2-methylsulfanyl-benzyl)-3H-imidazol-1-ium; bromide

There total 5 articles about 1-methyl-3-(2-methylsulfanyl-benzyl)-3H-imidazol-1-ium; bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

1-methyl-1H-imidazole (616-47-7) + 2-methylmercaptobenzyl bromide (89981-01-1) → 1-methyl-3-(2-methylsulfanyl-benzyl)-3H-imidazol-1-ium; bromide (914402-05-4)

Guidance literature:

In toluene; at 80 ℃;

DOI:10.1021/om9010966

Reference yield:

Thiosalicylic acid (147-93-3) → 1-methyl-3-(2-methylsulfanyl-benzyl)-3H-imidazol-1-ium; bromide (914402-05-4)

Guidance literature:

Multi-step reaction with 5 steps

1.1: NaOH / methanol

1.2: HCl / methanol

2.1: H₂SO₄

3.1: LiAlH₄ / tetrahydrofuran

3.2: H₂SO₄

4.1: PBr₃ / diethyl ether

5.1: toluene

With sodium hydroxide; lithium aluminium tetrahydride; phosphorus tribromide; sulfuric acid; In tetrahydrofuran; methanol; diethyl ether; toluene;

DOI:10.1039/b608325k

Reference yield:

2-(methylthio)benzoic acid (3724-10-5) → 1-methyl-3-(2-methylsulfanyl-benzyl)-3H-imidazol-1-ium; bromide (914402-05-4)

Guidance literature:

Multi-step reaction with 4 steps

1.1: H₂SO₄

2.1: LiAlH₄ / tetrahydrofuran

2.2: H₂SO₄

3.1: PBr₃ / diethyl ether

4.1: toluene

With lithium aluminium tetrahydride; phosphorus tribromide; sulfuric acid; In tetrahydrofuran; diethyl ether; toluene;

DOI:10.1039/b608325k

upstream raw materials:

1-methyl-1H-imidazole

2-methylmercaptobenzyl bromide

2-(methylthio)benzyl alcohol

methyl 2-(methylthio)benzoate