3-(2-bromoethyl)-1-benzylbenzimidazolium bromide salt

Base Information

• Chemical Name: 3-(2-bromoethyl)-1-benzylbenzimidazolium bromide salt
• CAS No.: 1192354-10-1
• Molecular Formula: Br*C₁₆H₁₆BrN₂
• Molecular Weight: 396.124
• Mol file: 1192354-10-1.mol

Synonyms:3-(2-bromoethyl)-1-benzylbenzimidazolium bromide salt

Chemical Property of 3-(2-bromoethyl)-1-benzylbenzimidazolium bromide salt

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 3-(2-bromoethyl)-1-benzylbenzimidazolium bromide salt

There total 3 articles about 3-(2-bromoethyl)-1-benzylbenzimidazolium bromide salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

1-benzylbenzimidazole (4981-92-4) + ethylene dibromide (106-93-4) → 3-(2-bromoethyl)-1-benzylbenzimidazolium bromide salt (1192354-10-1)

Guidance literature:

at 85 ℃;

DOI:10.1039/b907887h

Reference yield:

benzyl bromide (100-39-0) → 3-(2-bromoethyl)-1-benzylbenzimidazolium bromide salt (1192354-10-1)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium hydroxide / dimethyl sulfoxide / 3 h / 20 °C

2: neat (no solvent) / 8 h / 80 °C

With potassium hydroxide; In dimethyl sulfoxide;

DOI:10.1016/j.molstruc.2017.03.097

Reference yield:

benzoimidazole (51-17-2,79351-71-6) → 3-(2-bromoethyl)-1-benzylbenzimidazolium bromide salt (1192354-10-1)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium hydroxide / dimethyl sulfoxide / 3 h / 20 °C

2: neat (no solvent) / 8 h / Reflux

With potassium hydroxide; In dimethyl sulfoxide;

DOI:10.1016/j.molstruc.2020.128890

upstream raw materials:

1-benzylbenzimidazole

ethylene dibromide

benzyl bromide

benzoimidazole