N-benzyl-N-phenyl thioformamide

Base Information

• Chemical Name: N-benzyl-N-phenyl thioformamide
• CAS No.: 36325-43-6
• Molecular Formula: C₁₄H₁₃NS
• Molecular Weight: 227.33
• Mol file: 36325-43-6.mol

Synonyms:N-benzyl-N-phenyl thioformamide

Chemical Property of N-benzyl-N-phenyl thioformamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-benzyl-N-phenyl thioformamide

There total 4 articles about N-benzyl-N-phenyl thioformamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

N-benzylformanilide (16350-99-5) → N-benzyl-N-phenyl thioformamide (36325-43-6)

Guidance literature:

With Lawessons reagent; In tert-butyl methyl ether; at 20 ℃; for 24h; Inert atmosphere;

DOI:10.1021/om500603v

Reference yield:

Formanilid (103-70-8) → N-benzyl-N-phenyl thioformamide (36325-43-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: potassium hydroxide; tetra(n-butyl)ammonium hydrogensulfate / toluene / 2 h / 20 °C / Inert atmosphere

1.2: 3 h / 80 - 90 °C / Inert atmosphere

2.1: Lawessons reagent / tert-butyl methyl ether / 24 h / 20 °C / Inert atmosphere

With Lawessons reagent; tetra(n-butyl)ammonium hydrogensulfate; potassium hydroxide; In tert-butyl methyl ether; toluene;

DOI:10.1021/om500603v

Reference yield:

benzyl bromide (100-39-0) → N-benzyl-N-phenyl thioformamide (36325-43-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: potassium hydroxide; tetra(n-butyl)ammonium hydrogensulfate / toluene / 2 h / 20 °C / Inert atmosphere

1.2: 3 h / 80 - 90 °C / Inert atmosphere

2.1: Lawessons reagent / tert-butyl methyl ether / 24 h / 20 °C / Inert atmosphere

With Lawessons reagent; tetra(n-butyl)ammonium hydrogensulfate; potassium hydroxide; In tert-butyl methyl ether; toluene;

DOI:10.1021/om500603v

upstream raw materials:

Formanilid

benzyl bromide

N-benzylformanilide

Downstream raw materials:

N-Benzylaniline