p-Tolyl 1-thio-2,3,4,6-tetra-O-(trimethylsilyl)-β-D-glucopyranoside

Base Information

• Chemical Name: p-Tolyl 1-thio-2,3,4,6-tetra-O-(trimethylsilyl)-β-D-glucopyranoside
• CAS No.: 942043-17-6
• Molecular Formula: C₂₅H₅₀O₅SSi₄
• Molecular Weight: 575.077
• Mol file: 942043-17-6.mol

Synonyms:4-methylphenyl 2,3,4,6-tetrakis-O-trimethylsilyl-1-thio-β-D-glucopyranoside

Chemical Property of p-Tolyl 1-thio-2,3,4,6-tetra-O-(trimethylsilyl)-β-D-glucopyranoside

Chemical Property:

• Storage Temp.: 2-8°C

Purity/Quality:

95% ^*data from raw suppliers

4-Methylphenyl 1-thio-2,3,4,6-tetra-O-(trimethylsilyl)-b-D-glucopyranoside ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of p-Tolyl 1-thio-2,3,4,6-tetra-O-(trimethylsilyl)-β-D-glucopyranoside

There total 10 articles about p-Tolyl 1-thio-2,3,4,6-tetra-O-(trimethylsilyl)-β-D-glucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

chloro-trimethyl-silane (75-77-4) + p-methylphenyl 1-thio-β-D-glucopyranoside (1152-39-2) → 4-methylphenyl 2,3,4,6-tetrakis-O-trimethylsilyl-1-thio-β-D-glucopyranoside (942043-17-6)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; for 16h; Inert atmosphere;

Reference yield: 97.0%

→ 4-methylphenyl 2,3,4,6-tetrakis-O-trimethylsilyl-1-thio-β-D-glucopyranoside (942043-17-6)

Guidance literature:

Reference yield: 90.0%

p-methylphenyl 1-thio-β-D-glucopyranoside (1152-39-2) + 1,1,1,3,3,3-hexamethyl-disilazane (999-97-3) → 4-methylphenyl 2,3,4,6-tetrakis-O-trimethylsilyl-1-thio-β-D-glucopyranoside (942043-17-6)

Guidance literature:

With phosphotungstic acid; In dichloromethane; at 60 ℃; for 2h;

DOI:10.1055/s-0040-1705990

upstream raw materials:

chloro-trimethyl-silane

p-methylphenyl 1-thio-β-D-glucopyranoside

para-thiocresol

D-glucose pentaacetate

Downstream raw materials:

p-methylphenyl 4,6-O-benzylidine-3-O-(naphthalen-2-ylmethyl)-1-thio-β-D-glucopyranoside

4-methylphenyl 2-O-benzoyl-4,6-O-benzylidene-3-O-benzyl-1-thio-β-D-glucopyranoside

4-methylphenyl 2-O-acetyl-3-O-benzyl-4,6-O-benzylidine1-thio-β-D-galactopyranoside

C₃₀H₃₂O₇S