diethyl 1-(4-methylphenyl)-4-phenyl-1,4-dihydropyridine-3,5-dicarboxylate

Base Information

Chemical Name:diethyl 1-(4-methylphenyl)-4-phenyl-1,4-dihydropyridine-3,5-dicarboxylate
CAS No.:136886-13-0
Molecular Formula:C₂₄H₂₅NO₄
Molecular Weight:391.467
Hs Code.:

Synonyms:diethyl 1-(4-methylphenyl)-4-phenyl-1,4-dihydropyridine-3,5-dicarboxylate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of diethyl 1-(4-methylphenyl)-4-phenyl-1,4-dihydropyridine-3,5-dicarboxylate

Chemical Property:

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Technology Process of diethyl 1-(4-methylphenyl)-4-phenyl-1,4-dihydropyridine-3,5-dicarboxylate

There total 3 articles about diethyl 1-(4-methylphenyl)-4-phenyl-1,4-dihydropyridine-3,5-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 954374-78-8
ethyl (E)-3-(4-bromo-2-formylphenoxy)acrylate

: 100-52-7
benzaldehyde

: 106-49-0,12221-03-3
p-toluidine

: 954374-96-0
C₂₉H₃₀NO₇Br

: 136886-13-0
diethyl 1-(4-methylphenyl)-4-phenyl-1,4-dihydropyridine-3,5-dicarboxylate

: 1761-61-1
5-bromosalicyclaldehyde

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 3h;
DOI:10.1021/jo7013593

Reference yield: 39.7%

: 100-52-7
benzaldehyde

: 106-49-0,12221-03-3
p-toluidine

: 623-47-2
propynoic acid ethyl ester

: 136886-13-0
diethyl 1-(4-methylphenyl)-4-phenyl-1,4-dihydropyridine-3,5-dicarboxylate

Guidance literature:: In acetic acid; for 0.416667h; Heating;
DOI:10.1111/cbdd.12185

Reference yield:

: 1613-92-9,2272-45-9,116546-08-8,137432-02-1,137432-09-8
(E)-N-benzylidene-4-toluidine

: 623-47-2
propynoic acid ethyl ester

: 136886-13-0
diethyl 1-(4-methylphenyl)-4-phenyl-1,4-dihydropyridine-3,5-dicarboxylate

Guidance literature:: With scandium tris(trifluoromethanesulfonate); In various solvent(s); for 24h; Heating;
DOI:10.1016/j.tetlet.2007.11.003