ETHYL 6-CHLORO-7-AZAINDOLE-2-CARBOXYLATE

Base Information

Chemical Name:ETHYL 6-CHLORO-7-AZAINDOLE-2-CARBOXYLATE
CAS No.:287384-84-3
Molecular Formula:C10H9ClN2O2
Molecular Weight:224.647
Hs Code.:2933990090
Mol file:287384-84-3.mol

Synonyms:1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid, 6-chloro-, ethyl ester;ethyl 6-chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylate;

Suppliers and Price of ETHYL 6-CHLORO-7-AZAINDOLE-2-CARBOXYLATE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
ethyl6-chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylate
10mg
$ 45.00

SynChem
ETHYL 6-CHLORO-1H-PYRROLO[2,3-B]PYRIDINE-2-CARBOXYLATE 95%
1 g
$ 419.00

Crysdot
Ethyl6-chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylate 95+%
1g
$ 415.00

Chemenu
Ethyl6-chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylate 95%
1g
$ 392.00

American Custom Chemicals Corporation
ETHYL-6-CHLORO-1H-PYRROLO[2,3-B]PYRIDINE-2-CARBOXYLATE 95.00%
5MG
$ 499.63

Alichem
Ethyl6-chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylate
250mg
$ 181.44

Total 31 raw suppliers

Chemical Property of ETHYL 6-CHLORO-7-AZAINDOLE-2-CARBOXYLATE

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Refractive Index:1.637
Boiling Point:382.975 °C at 760 mmHg
Flash Point:185.417 °C
PSA：54.98000
Density:1.391 g/cm³
LogP:2.39300
Storage Temp.:2-8°C

Purity/Quality:

97% ^*data from raw suppliers

ethyl6-chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of ETHYL 6-CHLORO-7-AZAINDOLE-2-CARBOXYLATE

There total 10 articles about ETHYL 6-CHLORO-7-AZAINDOLE-2-CARBOXYLATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 26.0%

: 287384-84-3
6-chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid ethyl ester

(RS) 7-Chloro-1,2,3,4,10,10a-6-aza-hexahydropyrazino[1,2-a]-7-indole fumarate: (RS) 7-Chloro-1,2,3,4,10,10a-6-aza-hexahydropyrazino[1,2-a]-7-indole fumarate

Guidance literature:

Reference yield:

: 45644-21-1
6-chloropyridin-2-amine

: 287384-84-3
6-chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 5 steps

1.1: triethylamine / dichloromethane / 16 h / 20 °C

2.1: tert.-butyl lithium / hexane; tetrahydrofuran / 0.5 h / -78 °C

2.2: 4 h / -78 - 20 °C

3.1: hydrogenchloride / methanol / water / 5 h / 110 °C

4.1: 1,4-diaza-bicyclo[2.2.2]octane / palladium diacetate / N,N-dimethyl-formamide / 3 h / 110 °C / Inert atmosphere

5.1: hydrogenchloride / 16.5 h / 0 °C / Reflux

With 1,4-diaza-bicyclo[2.2.2]octane; hydrogenchloride; tert.-butyl lithium; triethylamine; methanol; palladium diacetate; In tetrahydrofuran; hexane; dichloromethane; water; N,N-dimethyl-formamide;