6-chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid

Base Information

Chemical Name:6-chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid
CAS No.:800402-07-7
Molecular Formula:C8H5ClN2O2
Molecular Weight:196.593
Hs Code.:2933990090
Mol file:800402-07-7.mol

Synonyms:1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 6-chloro-;acide 6-chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylique;

Suppliers and Price of 6-chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylicAcid
5g
$ 60.00

SynQuest Laboratories
6-Chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid 95%
100 mg
$ 104.00

SynQuest Laboratories
6-Chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid 95%
500 mg
$ 295.00

Matrix Scientific
6-Chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid >95%
1g
$ 1496.00

Matrix Scientific
6-Chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid >95%
250mg
$ 492.00

Matrix Scientific
6-Chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid >95%
500mg
$ 822.00

Labseeker
6-Chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylicacid 95
1g
$ 538.00

Crysdot
6-Chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylicacid 95+%
1g
$ 450.00

Chemenu
6-chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylicacid 95%+
1g
$ 221.00

Chemenu
6-chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylicacid 95%+
250mg
$ 95.00

Total 32 raw suppliers

Chemical Property of 6-chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Refractive Index:1.744
Boiling Point:467.036 °C at 760 mmHg
PKA:3.88±0.30(Predicted)
Flash Point:236.255 °C
PSA：65.98000
Density:1.644 g/cm³
LogP:1.91450
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

99%, ^*data from raw suppliers

6-chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 6-chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid

There total 1 articles about 6-chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 45644-21-1
6-chloropyridin-2-amine

: 800402-07-7
6-chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid

Guidance literature:: Multi-step reaction with 4 steps

1.1: triethylamine / dichloromethane / 16 h / 20 °C

2.1: tert.-butyl lithium / hexane; tetrahydrofuran / 0.5 h / -78 °C

2.2: 4 h / -78 - 20 °C

3.1: hydrogenchloride / methanol / water / 5 h / 110 °C

4.1: 1,4-diaza-bicyclo[2.2.2]octane / palladium diacetate / N,N-dimethyl-formamide / 3 h / 110 °C / Inert atmosphere

With 1,4-diaza-bicyclo[2.2.2]octane; hydrogenchloride; tert.-butyl lithium; triethylamine; methanol; palladium diacetate; In tetrahydrofuran; hexane; dichloromethane; water; N,N-dimethyl-formamide;

Reference yield: 37.0%

: 6850-57-3
2-methoxybenzylamine

: 800402-07-7
6-chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid

: 6-chloro-N-(2-methoxybenzyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide

Guidance literature:: With triethylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In dichloromethane;