5-chloro-N-(2-mesyloxyethyl)-2-nitroaniline

Base Information

• Chemical Name: 5-chloro-N-(2-mesyloxyethyl)-2-nitroaniline
• CAS No.: 100418-35-7
• Molecular Formula: C₉H₁₁ClN₂O₅S
• Molecular Weight: 294.716
• Mol file: 100418-35-7.mol

Synonyms:5-chloro-N-(2-mesyloxyethyl)-2-nitroaniline

Chemical Property of 5-chloro-N-(2-mesyloxyethyl)-2-nitroaniline

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 5-chloro-N-(2-mesyloxyethyl)-2-nitroaniline

There total 1 articles about 5-chloro-N-(2-mesyloxyethyl)-2-nitroaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

2-<(5-chloro-2-nitro)phenylamino>ethanol (50610-29-2) + methanesulfonyl chloride (124-63-0) → 5-chloro-N-(2-mesyloxyethyl)-2-nitroaniline (100418-35-7)

Guidance literature:

With pyridine; Ambient temperature;

DOI:10.1016/S0040-4020(01)89768-4

Reference yield: 92.0%

5-chloro-N-(2-mesyloxyethyl)-2-nitroaniline (100418-35-7) + potassium thioacyanate (333-20-0) → 5-chloro-2-nitro-N-(2-thiocyanatoethyl)-aniline (100418-41-5)

Guidance literature:

Heating;

DOI:10.1016/S0040-4020(01)89768-4

Reference yield:

5-chloro-N-(2-mesyloxyethyl)-2-nitroaniline (100418-35-7) → 4-Chloro-N2-(2-thiocyanato-ethyl)-benzene-1,2-diamine

Guidance literature:

Multi-step reaction with 2 steps

1: 92 percent / Heating

2: H₂ / 10percent Pd-C / Ambient temperature; normal pressure

With hydrogen; palladium on activated charcoal;

DOI:10.1016/S0040-4020(01)89768-4

upstream raw materials:

2-<(5-chloro-2-nitro)phenylamino>ethanol

methanesulfonyl chloride

Downstream raw materials:

5-chloro-2-nitro-N-(2-thiocyanatoethyl)-aniline

3-(2-amino-5-chlorophenyl)-2-iminothiazolidine dihydrochloride

Refernces

• 1、 -. "Iminothiazolidine derivatives". . . Retrieved 2008/06/13.