(E)-4-phenyl-3-butenamide

Base Information

• Chemical Name: (E)-4-phenyl-3-butenamide
• CAS No.: 26121-45-9
• Molecular Formula: C₁₀H₁₁NO
• Molecular Weight: 161.203
• Mol file: 26121-45-9.mol

Synonyms:(E)-4-phenyl-3-butenamide

Chemical Property of (E)-4-phenyl-3-butenamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-4-phenyl-3-butenamide

There total 10 articles about (E)-4-phenyl-3-butenamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

carbon monoxide (201230-82-2) + (E)-cinnamyl diethyl phosphate (85669-63-2) → (E)-4-phenyl-3-butenamide (26121-45-9)

Guidance literature:

With dmap; hexarhodium hexadecacarbonyl; ammonium chloride; triethylamine; In dimethyl sulfoxide; at 50 ℃; for 6h; under 15200 Torr;

DOI:10.1016/0022-328X(93)83025-Q

Reference yield: 58.0%

C15H19N3O → (E)-4-phenyl-3-butenamide (26121-45-9)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 ℃; for 0.166667h;

DOI:10.1246/cl.130195

Reference yield: 58.0%

trans-3-phenylprop-2-enyl chloride (21087-29-6) + carbon monoxide (201230-82-2) → (E)-4-phenyl-3-butenenitrile (20068-10-4) + (1E,5E)-1,6-diphenyl-1,5-hexadiene (58463-02-8) + (E)-4-phenyl-3-butenamide (26121-45-9)

Guidance literature:

With tri-tert-butyl phosphine; titanium-nitrogen; potassium carbonate; palladium diacetate; In N,N,N,N,N,N-hexamethylphosphoric triamide; toluene; at 20 ℃; Further Variations:; Reagents; Solvents; Product distribution;

DOI:10.1016/j.tetlet.2004.02.072

upstream raw materials:

carbon monoxide

(E)-cinnamyl diethyl phosphate

benzyl tri-n-butylammonium bromide

2-propenamide

Downstream raw materials:

(E)-4-phenylbut-3-enethioamide

4-phenylbutyramide

(E)-4-phenylbut-3-en-1-amine

trans-styrylacetic acid