(E)-4-phenylbut-3-en-1-amine

Base Information

• Chemical Name: (E)-4-phenylbut-3-en-1-amine
• CAS No.: 7515-38-0
• Molecular Formula: C10H13N
• Molecular Weight: 147.22
• DSSTox Substance ID: DTXSID10467165
• Nikkaji Number: J1.524.441K
• Wikidata: Q82293974
• Mol file: 7515-38-0.mol

Synonyms:82593-25-7;4-Phenylbut-3-en-1-amine;(E)-4-phenylbut-3-en-1-amine;(3E)-4-phenylbut-3-en-1-amine;7515-38-0;4-Phenyl-3-buten-1-amine;4-Phenyl-3-butene-1-amine;SCHEMBL1536706;SCHEMBL1829198;DTXSID10467165;MFCD08448819;AKOS011839219;NS-01127;CS-0269706;F15194;EN300-1244408

Chemical Property of (E)-4-phenylbut-3-en-1-amine

Chemical Property:

• Vapor Pressure: 0.01mmHg at 25°C
• XLogP3: 1.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 147.104799419
• Heavy Atom Count: 11
• Complexity: 112

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C=CCCN
• Isomeric SMILES: C1=CC=C(C=C1)/C=C/CCN

Technology Process of (E)-4-phenylbut-3-en-1-amine

There total 9 articles about (E)-4-phenylbut-3-en-1-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

(E)-4-phenyl-3-butenamide (26121-45-9) → (E)-4-phenylbut-3-en-1-amine (7515-38-0)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; for 3h; Ambient temperature;

DOI:10.1016/0022-328X(93)83025-Q

Reference yield: 13.0%

N-(4-phenyl-3-butenyl)phthalimide (143741-67-7) → 4-phenyl-1-butylamine (13214-66-9) + (E)-4-phenylbut-3-en-1-amine (7515-38-0) + (Z)-4-phenylbut-3-en-1-amine (93085-47-3)

Guidance literature:

With hydrazine hydrate; In ethanol; at 20 ℃; for 10h; optical yield given as %de;

DOI:10.1080/00397910802369596

Reference yield:

benzaldehyde (100-52-7) + (3-aminopropyl)(triphenyl)phosphonium bromide (89996-01-0) → (E)-4-phenylbut-3-en-1-amine (7515-38-0)

Guidance literature:

With n-butyllithium; In tetrahydrofuran; for 15h;

DOI:10.1021/ja00287a040

upstream raw materials:

4-phenyl-3-butenyl para-toluenesulfonate

benzaldehyde

(3-aminopropyl)(triphenyl)phosphonium bromide

(E)-4-phenyl-3-butenamide

Downstream raw materials:

3-chloro-propionic acid-(4t-phenyl-but-3-enylamide)

(E)-4-methyl-N-(4-phenylbut-3-en-1-yl)benzenesulfonamide

N-(E)-(4-phenylbut-3-en-1-yl)acetamide

Naphthalin-2-sulfonsaeure-<4-phenyl-but-3-en-1-ylester>