2S-[[(dimethylamino)-acetyl] amino]-N-[2R-hydroxy-3-[(3-methylbutyl)-(phenylsulfonyl)amino]-1S-(phenylmethyl) propyl]-3,3-dimethylbutaneamide

Base Information

• Chemical Name: 2S-[[(dimethylamino)-acetyl] amino]-N-[2R-hydroxy-3-[(3-methylbutyl)-(phenylsulfonyl)amino]-1S-(phenylmethyl) propyl]-3,3-dimethylbutaneamide
• CAS No.: 159005-93-3
• Molecular Formula: C₃₁H₄₈N₄O₅S
• Molecular Weight: 588.812

Synonyms:2S-[[(dimethylamino)-acetyl] amino]-N-[2R-hydroxy-3-[(3-methylbutyl)-(phenylsulfonyl)amino]-1S-(phenylmethyl) propyl]-3,3-dimethylbutaneamide

Chemical Property of 2S-[[(dimethylamino)-acetyl] amino]-N-[2R-hydroxy-3-[(3-methylbutyl)-(phenylsulfonyl)amino]-1S-(phenylmethyl) propyl]-3,3-dimethylbutaneamide

Chemical Property:

Purity/Quality:

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Technology Process of 2S-[[(dimethylamino)-acetyl] amino]-N-[2R-hydroxy-3-[(3-methylbutyl)-(phenylsulfonyl)amino]-1S-(phenylmethyl) propyl]-3,3-dimethylbutaneamide

There total 2 articles about 2S-[[(dimethylamino)-acetyl] amino]-N-[2R-hydroxy-3-[(3-methylbutyl)-(phenylsulfonyl)amino]-1S-(phenylmethyl) propyl]-3,3-dimethylbutaneamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2S-[[(dimethylamino)acetyl]amino]-N-[2R-hydroxy-3-[(3-methylbutyl) (methylsulfonyl)amino]-1S-(phenylmethyl)propyl]-3,3-dimethylbutanamide (159006-07-2) + N,N-dimethylammonium chloride (506-59-2) → 2S-[[(dimethylamino)-acetyl] amino]-N-[2R-hydroxy-3-[(3-methylbutyl)-(phenylsulfonyl)amino]-1S-(phenylmethyl) propyl]-3,3-dimethylbutaneamide (159005-93-3)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In methanol; dichloromethane;

Reference yield:

(S)-N-carbobenzoxy-tert-butylleucine (62965-10-0) + benzotriazol-1-ol (2592-95-2) → phenylmethyl [1S-[[[2R-hydroxy-3-[(3-methylbutyl) (phenylsulfonyl)amino]-1S-(phenylmethyl)propyl]amino] carbonyl]-2,2-dimethylpropyl]carbamate (159006-10-7) + 2S-[[(dimethylamino)-acetyl] amino]-N-[2R-hydroxy-3-[(3-methylbutyl)-(phenylsulfonyl)amino]-1S-(phenylmethyl) propyl]-3,3-dimethylbutaneamide (159005-93-3)

Guidance literature:

With sodium hydrogencarbonate; 1,2-dichloro-ethane; In hexane; ethyl acetate; N,N-dimethyl-formamide;

upstream raw materials:

(S)-N-carbobenzoxy-tert-butylleucine

benzotriazol-1-ol

2S-[[(dimethylamino)acetyl]amino]-N-[2R-hydroxy-3-[(3-methylbutyl) (methylsulfonyl)amino]-1S-(phenylmethyl)propyl]-3,3-dimethylbutanamide

N,N-dimethylammonium chloride

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