4-CHLOROBENZALDEHYDE DIMETHYL ACETAL 9&

Base Information

• Chemical Name: 4-CHLOROBENZALDEHYDE DIMETHYL ACETAL 9&
• CAS No.: 3395-81-1
• Molecular Formula: C9H11 Cl O2
• Molecular Weight: 186.638
• Mol file: 3395-81-1.mol

Synonyms:Benzaldehyde,p-chloro-, dimethyl acetal (7CI,8CI); 1-Chloro-4-(dimethoxymethyl)benzene;4-Chlorobenzaldehyde dimethyl acetal; p-Chlorobenzaldehyde dimethyl acetal

Chemical Property of 4-CHLOROBENZALDEHYDE DIMETHYL ACETAL 9&

Chemical Property:

• Vapor Pressure: 0.282mmHg at 25°C
• Refractive Index: n20/D 1.508(lit.)
• Boiling Point: 114-115 °C19 mm Hg(lit.)
• Flash Point: 215 °F
• PSA: 18.46000
• Density: 1.128 g/mL at 25 °C(lit.)
• LogP: 2.63140
• Storage Temp.: 2-8°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-Chlorobenzaldehyde dimethyl acetal 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of 4-CHLOROBENZALDEHYDE DIMETHYL ACETAL 9&

There total 21 articles about 4-CHLOROBENZALDEHYDE DIMETHYL ACETAL 9& which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methanol (67-56-1) + 4-chlorobenzaldehyde (104-88-1) → 4-chlorobenzaldehyde dimethyl acetal (3395-81-1)

Guidance literature:

antimony(III) chloride; iron; for 12h; Ambient temperature;

DOI:10.1016/S0040-4020(01)85467-3

Reference yield: 99.5%

4-chlorobenzaldehyde (104-88-1) + trimethyl orthoformate (149-73-5) → 4-chlorobenzaldehyde dimethyl acetal (3395-81-1)

Guidance literature:

With amberlyst-15; In acetonitrile; for 1h; electroosmos;

DOI:10.1039/b614559k

Reference yield: 94.2%

methanol (67-56-1) + 4-chlorobenzaldehyde (104-88-1) + trimethyl orthoformate (149-73-5) → 4-chlorobenzaldehyde dimethyl acetal (3395-81-1)

Guidance literature:

With povidone-iodine; at 30 ℃; for 3h; Time; Temperature; Catalytic behavior; Green chemistry;

DOI:10.1016/j.tet.2021.132250

upstream raw materials:

methanol

4,4'-((4-chlorophenyl)methylene)dimorpholine

4-chlorobenzaldehyde

N,N-dimethylformamide dimethyl sulfate adduct

Downstream raw materials:

(α,4-Dichlorbenzyl)methylether

1-(4-chlorophenyl)-1-methoxyhept-2-yne

1-Chloro-4-(1,3,3-trimethoxy-propyl)-benzene

5-[2-(4-Chloro-phenyl)-2-methoxy-ethyl]-2-methoxy-2,4-dimethyl-2,3-dihydro-benzo[b]oxepine

Refernces

• 1、 Wang, Xinglin,Li, Yuanyuan,Li, Zhaohui. "Thiol-initiated photocatalytic oxidative cleavage of the C=C bond in olefins and its extension to direct production of acetals from olefins". . p. 1000 - 1006. Retrieved 2021/02/26.
• 2、 Kokotos, Christoforos G.,Nikitas, Nikolaos F.,Spiliopoulou, Nikoleta. "Photochemical synthesis of acetals utilizing Schreiner's thiourea as the catalyst". supporting information. p. 3539 - 3545. Retrieved 2020/06/25.