2-(Dimethylamino)-5-nitrobenzaldehyde

Base Information

• Chemical Name: 2-(Dimethylamino)-5-nitrobenzaldehyde
• CAS No.: 34601-40-6
• Molecular Formula: C9H10 N2 O3
• Molecular Weight: 194.19
• Hs Code.: 2922399090
• DSSTox Substance ID: DTXSID50401285
• Wikidata: Q82204355
• Mol file: 34601-40-6.mol

Synonyms:2-(dimethylamino)-5-nitrobenzaldehyde;34601-40-6;2-(Dimethylamino)-5-nitrobenzenecarbaldehyde;DTXSID50401285;MFCD04085744;AKOS000416229;KB-0723;CS-0259181;FT-0681152;EN300-725703;J-506391;Z57727225

Chemical Property of 2-(Dimethylamino)-5-nitrobenzaldehyde

Chemical Property:

• Vapor Pressure: 7E-05mmHg at 25°C
• Melting Point: 103-105°C
• Refractive Index: 1.632
• Boiling Point: 343.5°Cat760mmHg
• Flash Point: 161.6°C
• PSA: 66.13000
• Density: 1.286g/cm³
• LogP: 1.99650
• XLogP3: 1.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 194.06914219
• Heavy Atom Count: 14
• Complexity: 225

Purity/Quality:

98%min ^*data from raw suppliers

2-(Dimethylamino)-5-nitrobenzaldehyde ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)C1=C(C=C(C=C1)[N+](=O)[O-])C=O

Technology Process of 2-(Dimethylamino)-5-nitrobenzaldehyde

There total 4 articles about 2-(Dimethylamino)-5-nitrobenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

dimethyl amine (124-40-3) + 2-chloro-5-nitrobenzaldehyde (6361-21-3) → 2-dimethylamino-5-nitrobenzaldehyde (34601-40-6)

Guidance literature:

In water; N,N-dimethyl-formamide; at 50 ℃; for 2h;

DOI:10.1070/MC2006v016n01ABEH002216

Reference yield:

tetrakis(dimethylamido)titanium(IV) + C13H13N3O3 → 2-dimethylamino-5-nitrobenzaldehyde (34601-40-6)

Guidance literature:

In dichloromethane; at 20 ℃; for 2h;

DOI:10.1021/acs.orglett.5b01229

Reference yield:

ethanol (64-17-5) + dimethyl amine (124-40-3) + 2-chloro-5-nitrobenzaldehyde (6361-21-3) → 2-dimethylamino-5-nitrobenzaldehyde (34601-40-6)

Guidance literature:

upstream raw materials:

ethanol

dimethyl amine

2-chloro-5-nitrobenzaldehyde

Refernces

• 1、 Krasnov, Konstantin A.,Kartsev, Viktor G.,Khrustalev, Victor N.. "Interaction of barbituric acids with o-dialkylaminobenzaldehydes". . p. 52 - 54. Retrieved 2007/10/03.